“…To date, the widely accepted gold standard is to extensively resect the infected aorta, aggressively debride the periaortic tissues, and reconstruct the aortic flow using extra-anatomic or anatomic bypass prosthetic grafts. 4,7 The biggest advantage of open surgery is that extensive debridement and excision of infected aortic tissue is still the optimal way to eradicate the source of infection; however, even after aggressive debridement, it is difficult to ensure that no microinfected nidus remains or to guarantee that the new prosthetic grafts will not be reinfected. Even in the last decade, up to 30% to 40% in-hospital mortality, depending on the location of the aneurysm and the severity of systemic inflammation, has been reported after open surgical management.…”