“…However, its limited availability, as well as the donor site morbidity and complications such as chronic pain, neurovascular injury and infection have dictated the need for the development of alternative methods of biological stimulation [3,15,17,24,34,35,39,49,96,105,112]. Other methods of biological stimulation, used either alone or in combination, include allo-grafting, the use of electrical, ultrasound, and shockwave stimulation, a variety of bone graft substitutes, with either osteoconductive or both osteoconductive and osteoinductive properties and bone marrow injections [26,52,73,84,87,90,122].…”