Diverticula of the duodenum are found on up to 5% of barium meals [1], 22% of autopsies [2], and approximately 10% to 15% of patients undergoing endoscopic retrograde cholangiopancreatography (ERCP) [3]. Duodenal diverticula are a mucosal outpouching that most often arise from the medial wall of the second part of the duodenum and the majority are juxtapapillary [4]. They may cause some difficulties in endoscopic cannulation, especially when the papilla is situated inside or on the ridge of a diverticulum [5]. In the literature, different impressions and controversial views are expressed on the success rate for cannulation and endoscopic sphincterotomy of the papilla in the presence of diverticula (L) [6][7][8][9][10][11][12][13]. This is a case report of acute biliary pancreatitis due to gallstones with a papilla situated inside a large diverticulum.
Case ReportAn 81-year-old Saudi female presented to the Accident and Emergency Room complaining of right upper quadrant and epigastric pain, recurrent vomiting and loss of appetite. Her family noticed her to be jaundiced for one day. She complained of constipation, but had no history of fever or chills, hematemesis or melena. She has a past history of myocardial infarction three years ago and trauma to the lumbar spine one year ago.On examination, this was an elderly thin female who looked ill, was in pain, mildly dehydrated, jaundiced and in distress. Temperature was 35.5°C, pulse 84/min and blood pressure 114/50 with no lymphadenopathy, no thyroid enlargement; chest and central nervous system were within normal limits. The cardiovascular system showed S1 and S2 and a pansystolic murmur. The abdomen was not distended; guarding with tenderness was present in the right upper quadrant. There were no masses or organomegaly. She has kyphoscoliosis.
InvestigationsOn admission, WBC was 12.2x10 9 /L, Hb 12.5 g/L, platelets 253x10 9 /L, total protein 66 g/L, albumin 34 g/L, total bilirubin 116 (μmol/L, bilirubin 95 μmol/L, aspartate transaminase 178 u/L, amylase 7,820 u/L, urea 8.6 μmol/L, Na 140 μmol/L, bicarbonate 24 μmol/L, creatinine 81 μmol/L, calcium 2.18 μmol/L, phosphate 1.32 μmol/L. Arterial blood gases showed a pH of 7.45 Kpa, PCO 2 5.03 Kpa, PO 2 11.09, O 2 saturation 0.96, PT 16/16, PTT 21/32, HbsAg +ve, HbcAb +ve, and mid stream urinalysis was negative.On the first day after admission, the patient had an ultrasound which showed dilatation of the common bile duct (1.1 cm) and shadowing in the distal common duct suggestive of a stone. The pancreas was not significantly enlarged or edematous, though there was slight dilatation of the pancreatic duct. The gallbladder wall was thickened and there were echoes within the gallbladder with some shadowing distally suggestive of calculi. The kidneys appeared normal. Abdominal x-ray showed no obvious abnormality apart from lumbar scoliosis. Chest x-ray showed slightly hyperinflated lungs, otherwise no active disease. X-ray of the lumbar spine showed severe scoliosis of the lumbar spine convex to the left. There were moder...