Surgical management of esophageal motility disorders

Woltman, Todd; Oelschlager, Brant K.

doi:10.1016/j.jss.2003.11.015

Cited by 8 publications

(15 citation statements)

References 42 publications

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“…Laparoscopic myotomy is currently recognized as the most effective way of relieving dysphagia in patients with achalasia 35 . There are two main points of controversy concerning this procedure: the length and site of the myotomy, and the need to incorporate an antireflux procedure 35 .…”

Section: Discussionmentioning

confidence: 99%

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Mechanisms controlling function in the clasp and sling regions of porcine lower oesophageal sphincter

Farré

Aulí

Lecea

et al. 2007

British Journal of Surgery

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Section: Discussionmentioning

confidence: 99%

“…There are two main points of controversy concerning this procedure: the length and site of the myotomy, and the need to incorporate an antireflux procedure 35 . There appears to be a high rate of postoperative dysphagia and gastro-oesophageal reflux 36 with a 'short' myotomy that includes 5-7 cm above and 0·5 cm below the LOS.…”

Section: Discussionmentioning

confidence: 99%

Mechanisms controlling function in the clasp and sling regions of porcine lower oesophageal sphincter

Farré

Aulí

Lecea

et al. 2007

British Journal of Surgery

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“…It is an uncommon ailment with a reported incidence of 0.5-1 per 100,000 in the United States (6). The clinical result of achalasia is insufficient LES relaxation and ineffective peristalsis, which leads to an inability to clear material from within the esophagus.…”

Section: Achalasiamentioning

confidence: 99%

Bioadhesive Dosage Forms for Esophageal Drug Delivery

Batchelor

2005

Pharm Res

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The esophagus as a site for drug delivery has been much overlooked in comparison to the remainder of the gastrointestinal tract. The low permeability and transient nature of the esophagus means that it is unsuitable for delivery of drugs for systemic action. However, esophageal disorders including fungal infection, cancers, motility dysfunction, and damage due to gastric reflux may be treated using locally acting agents that offer benefits of reduced dosage and decreased side effects. Bioadhesive dosage forms that adhere to the esophageal mucosa and prolong contact have been investigated to improve the efficacy of locally acting agents. The rationale for local esophageal drug delivery and its limitations, the factors that determine adhesion to this organ, and the experimental models used in esophageal drug delivery research are reviewed.

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“…Disease presented with progressive dysphagiaanda have various degrees of weight loss, chest pain, aspiration and regurgitation (1)(2)(3)(4). Although the disease has been known for more than 300 years ago, but its cause remains unknown.…”

Section: Introductionmentioning

confidence: 99%

Laparoscopic Heller Myotomy and Dor Fundoplication: Prospective Evaluation of 30 Consecutive Patients

Mohajeri

Mahmoudieh

Keleidari

et al. 2016

J Minim Invasive Surg Sci

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Background: Prospective studies evaluating outcome of laparoscopic Heller myotomy and Dor fundoplication for esophageal achalasia are less in Asian people. Objectives: This study conducted to evaluate the results of laparoscopic cardiomyotomy and partial fundoplication for achalasia. Patients and Methods: Thirty patients who underwent Heller myotomy for achalasia via laparoscopy in Alzahra hospital Isfahan, Iran were recorded prospectively (2009 -2013). Median follow-up was 18 months. Symptoms including dysphagia, regurgitation, chest pain and weight loss were recorded before and after operation. Also, previous treatment for achalasia such as endoscopic pneumatic dilatations and intrasphincteric injection of botulinum toxin or other component, duration of symptoms and duration and complication of operation was recorded. Results: Among 30 patients, there were 13 (43.3%) females and 17 (56.7%) males, and mean age was 40.8 years (range, 20 -68 years).

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Surgical management of esophageal motility disorders

Cited by 8 publications

References 42 publications

Mechanisms controlling function in the clasp and sling regions of porcine lower oesophageal sphincter

Mechanisms controlling function in the clasp and sling regions of porcine lower oesophageal sphincter

Bioadhesive Dosage Forms for Esophageal Drug Delivery

Laparoscopic Heller Myotomy and Dor Fundoplication: Prospective Evaluation of 30 Consecutive Patients

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