Surgical Management of Intracranial Gliomas

A, Ley; Guitart, J. Morera; Oliveras, Clara

doi:10.3171/jns.1962.19.5.0365

Cited by 32 publications

(10 citation statements)

References 10 publications

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“…The quality of survival has been inadequately dealt with in previous reviews, so close comparison with the present results cannot be made. Ley et al (1962) in a paper from Barcelona emphasize the difficulty which surgeons in some countries have in following up their patients. Bettag (1959) reviewed 251 glioblastoma multiforme tumours and found that for those patients surviving more than two months after operation 17-2% returned to full work, 26-5 % to partial work, 28&5 % were unemployed, and 27-8 % were in need of nursing care.…”

Section: Discussionmentioning

confidence: 99%

“…In the last decade, reviews of large series, consisting mainly of cases of glioblastoma multiforme, have been given by Davis, Martin, Goldstein, and Askenazy (1949), Penman and Smith (1954), Frankel and German (1958), Tonnis and Walter (1959), Bettag (1959), Roth and Elvidge (1960), and Ley, Ley, Guitart, and Oliveras (1962). These have been concerned with detailed analyses of symptoms and signs and the duration of post-operative survival, but the quality of survival has been only briefly mentioned.…”

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confidence: 99%

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Quality of survival in treated patients with supratentorial gliomata

Betty¹

1964

Journal of Neurology, Neurosurgery & Psychiatry

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Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

Quality of survival in treated patients with supratentorial gliomata

Betty¹

1964

Journal of Neurology, Neurosurgery & Psychiatry

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“…Many methods of treating gliomas have been tried, e.g. partial or complete removal by surgery [24][25][26][27][28][29][30][31][32][33][34], chemotherapy [35][36][37], surgery and irradiation, and a combination of all three [38][39][40][41]. In recent years the immuno-therapy [42] and the antibody guided irradiation of brain glioma have been reported [43].…”

Section: Discussionmentioning

confidence: 99%

Application of invasive microwave hyperthermia for the treatment of gliomas

et al. 1988

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Twenty five cases of gliomas of the brain were operated upon by debulking the tumour masses. Following this, microwave hyperthermia was given by heating a measured volume of Ringer's solution instilled into the tumour cavity. This was followed by a 'dry treatment' without Ringer's solution. The follow up of these cases revealed that 11 cases have died and 14 cases are alive post-operatively. For those that are alive, the follow up period ranges from 21 to 41 months with the mean survival period of 31.1 months; in this group, 12 cases have a Kanofsky scale of 80-100, i.e. they are fully independent. The other two cases have a score of 50 or under and they need institutional care. In this study, we believe that the first order effect of microwave hyperthermia is predominantly thermal and in the published literature, and in this investigation, there is no clear evidence that microwave radiation produces any other beneficial and quantifiable effect on the tissue.

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“…In the posterior cranial fossa complete tumor removal is almost [14,20,30] -if not absolutely [5,22,28,29] -impossible, because ependymomas usually originate from the floor of the fourth ventricle [24,35] and thus have a close relation to the vital centres of the brain stem. Only when the insertion is very small in diameter or the tumor arises from the roof of the fourth ventricle, is a complete resection possible [17,24].…”

Section: Discussionmentioning

confidence: 99%

Intracranial ependymomas: Prognostic aspects

1989

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According to the grading of brain tumors as proposed by the WHO in 1976, out of 128 ependymomas 83 tumors could be classified as grade II and 38 as grade III Only seven subependymomas were benign and could be assigned to grade I. In contrast to most series known from the literature, 73 ependymomas were located above the tentorium and only 55 in the posterior cranial fossa. The grade of malignancy rised with an increased distance from the ventricular level. Macroscopically complete exstirpations were usually possible in hemispheric ependymomas, whereas tumors arising from the floor of the fourth ventricle often allowed only a partial removal. The operative mortality in the infratentorial group was more than twice as that in the supratentorial group. Postoperative survival was predominantly dependent on the histologic grade of malignancy. The five year survival rate without recurrence was 57.4% in grade II ependymomas as compared to 24.1% in grade III ependymomas. It could be improved by postoperative radiation therapy in both groups of malignancy. The almost identical longterm results indicate that even in less malignant ependymomas new tumor growth will occur later on.

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Surgical Management of Intracranial Gliomas

Cited by 32 publications

References 10 publications

Quality of survival in treated patients with supratentorial gliomata

Quality of survival in treated patients with supratentorial gliomata

Application of invasive microwave hyperthermia for the treatment of gliomas

Intracranial ependymomas: Prognostic aspects

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