Surgical management of primary thyroid carcinoma arising in thyroglossal duct cyst: An experience of a single institution in Serbia

Lymphatic drainage, regional metastases and surgical management of papillary thyroid carcinoma arising in pyramidal lobe – a single institution experience

“…Our surgical strategy in managing lateral neck compartment is based on sentinel LN biopsy as a standard procedure for PTC in our institution [34]. If sentinels are proven to be malignant, levels II -V dissection is performed -otherwise, no MRND is necessary [30,34]. In our study, all analyzed sentinels were benign (both in frozen section and standard pathology), thus no MRND was performed.…”

“…Initial CND prevents central recurrence of the malignant disease [25][26][27]. Re-operations in central compartment, in comparison to initial surgery, more often lead to persistent hypoparathyroidism and RLN injury [16,[28][29][30]. On the other hand, there are no differences in the rates of permanent hypoparathyroidism or RLN injury between groups of patients with and without initial CND [31].…”

Thyroglossal Duct Cyst Carcinomas: A Clinicopathologic Series of 22 Cases with Staging Recommendations

“…Following adequate excision of the lesion, there are divergent opinions regarding further clinical management of patients with TGDC malignancies [23,24]. While prior studies have concluded that the Sistrunk procedure alone represents adequate therapy for TGDCCa [18,19,21], others advocate the need for total thyroidectomy in all patients based on data reporting a potentially high risk of unsuspected thyroid gland involvement by a synchronous intrathyroidal papillary thyroid carcinoma [5,13,22,24,28,31]. Thyroidectomy also allows for the option of radio ablative iodine therapy and more effective use of serum thyroglobulin levels for clinical surveillance.…”

“…They are generally indolent tumors with a small potential for locoregional recurrence [8, 10, 14, 15, 22, 25, 28, 30-32, 34, 35]. While no patients in this cohort had an adverse outcome, there have been rare reported cases of distant metastases and disease related mortality [10,25,31,35].…”

Papillary carcinoma thyroid in a thyroglossal cyst: A management dilemma

“…On the contrast, Hartl [25] could find carcinomatous foci in the thyroid lobes in 3 out of 18 cases. Dzodic et al [26] reported a 25% rate of detecting a lesion in the thyroidectomy specimen. In low-risk cases age <45 years, cyst size less than 4 cm, no extra capsular infiltration and no neck node Sistrunk's operation only will suffice but requires regular and close follow up.…”