Surgical management of soft tissue tumors of the abdominal wall: A retrospective study in a high‐volume sarcoma center

Abstract

Background The aim of the study is to evaluate functional and oncological outcomes of patients undergoing abdominal wall soft tissue tumors (AWSTT) surgery. Methods All consecutive patients that underwent surgery for malignant and intermediate AWSTT from 1999 to 2019 were retrospectively analyzed. Results Ninety‐two patients were identified, 20 (22%) operated on for a desmoid tumor and 72 (78%) for a soft tissue sarcoma (STS). Fifty‐two patients (57%) had in toto resection of the abdominal wall (from the skin to the peritoneum) and 9 (10%) required simultaneous visceral resection. The closure was direct in 28 patients (30%) and requiring a mesh, a flap or a combination of the two in respectively 42, 16, and 6 patients (47%, 17%, 6%). The postoperative complications rate was 26%. Thirteen patients (14%) developed an incisional hernia after a median delay of 27 months. After a median follow‐up of 40 months, out of the 72 patients operated on for STS, 7 (10%) developed local recurrence and 11 (15%) distant recurrence. The median recurrence‐free and overall survivals were 61 and 116, months respectively. Conclusions Management of AWSTT requires extensive surgery but allows good local control with an acceptable rate of incisional hernia.

MPNST of the abdominal wall in a patient with lynch syndrome: A case report of a rare presentation and unique association

“…It is also believed that anatomical barriers limit the spread of these tumors and can be respected when not invaded. Sometimes even en-bloc resections (bone, intra-abdominal organs, inguinal ligament resections) with full-thickness abdominal wall resection cannot ensure clear margins of 1 mm but are not associated with higher local recurrence [ 10 ]. The abdominal defect is managed by direct closure, flaps, or the use of prosthetic mesh.…”

“…Direct closure can be preferred for tumors less than 8 cm. The use of prosthetic mesh is associated with a higher rate of postoperative complications since abdominal wall soft tissue tumor surgery tends to have a high risk of infection by itself [ 10 ].…”

Overall survival in abdominal wall sarcoma treated with curative intent surgery: A retrospective study from two European referral centres

“…Stojadinovic et al 2 reported a longer median time to recurrence of 10 months in a series of abdominal wall sarcomas with a 5‐year DFS of 75% and a distant metastatic rate of 25%. A recent paper by Neuberg et al 17 described surgical outcomes in patients with DFSP and abdominal wall sarcomas treated at a single centre. They reported outcomes of 72 patients with 5‐year OS and DFS as 84% and 59%, respectively, a local recurrence rate of 10% and a distant metastatic rate of 15% at 40 months.…”

Pleomorphic Rhabdomyosarcoma: A Systematic Review with Outcome Analysis and Report of a Rare Abdominal Wall Lesion

“…1,15 We performed a literature review of the soft tissue sarcomas of the abdominal wall and found 50-60% of neoplasms were fibromatosis with adipocytic tumors, smooth muscle tumors, and fibroblastic tumors comprising rest of the share, while tumors displaying skeletal muscle differentiation are exceedingly rare. [15][16][17][18][19][20][21][22][23][24] Due to the scattered nature of the data on abdominal wall sarcomas and the lack of existing systematic analyses of these tumors, it is impossible to exactly specify the percentage of RMS or pleomorphic RMS among these tumors.…”