Surgical management of the duodenal manifestations of familial adenomatous polyposis

Abstract

Surgery should be reserved for advanced or malignant polyps.

Duodenal surveillance improves the prognosis after duodenal cancer in familial adenomatous polyposis

“…Repeated endoscopic mucosal resection with argon plasma coagulation has recently been used without major complications in selected patients with large duodenal polyps or plaques, resulting in downstaged adenomatosis [10], but large prospective studies are needed to allow a definite evaluation of this treatment option. At present, surgery is therefore the recommended cancer prophylaxis, although endoscopic treatment may be used in selected patients [24].…”

S3-Leitlinie – Kolorektales Karzinom

“…Aufgrund des hohen Karzinomrisikos im Spigelman-Stadium IV muss hier ein chirurgisches Vorgehen empfohlen werden, wobei der pankreaserhaltenden Duodenektomie, auch aufgrund der geringeren Morbiditätsrate gegenüber der Pankreatikoduodenektomie der Vorzug zu geben ist [319,320].…”

Familial Colon Cancer Syndromes: an Update of a Rapidly Evolving Field

“…Most practitioners perform surveillance and remove adenomatous lesions endoscopically, reserving surgery for large lesions or cancer. Parc et al (39) performed a retrospective review of the literature from 1965 to 2009 and reported that recurrence rates did not appear to differ between endoscopic removal and transduodenal resection of duodenal adenomas.…”