Surgical outcomes and quality of life post‐synthetic mesh‐augmented repair for pelvic organ prolapse in the <scp>C</scp>hinese population

Sun, Xiuli; Zhang, Xiaowei; Wang, Jianliu

doi:10.1111/jog.12167

Cited by 4 publications

(2 citation statements)

References 18 publications

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“…[17] This result was possibly relevant to the unidentified defect during operation. Nevertheless, previous studies reported that the recurrence rate of synthetic mesh repair was 4%–15%,[1819] which was much lower than that after SIS repair. The reason for the variance might be the better stability of synthetic mesh.…”

Section: Discussionmentioning

confidence: 91%

Porcine Small Intestinal Submucosa Mesh for Treatment of Pelvic Organ Prolapsed

Cao

Sun

Wang

et al. 2016

Chinese Medical Journal

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Background:Pelvic organ prolapse (POP) is a major health concern that affects women. Surgeons have increasingly used prosthetic meshes to correct POP. However, the most common used is synthetic mesh, and absorbable mesh is less reported. This research aimed to evaluate the clinical effectiveness of porcine small intestinal submucosa (SIS).Methods:Consecutive forty POP patients who met the inclusion criteria underwent pelvic reconstruction surgery with SIS between March 2012 and December 2013. The patients’ clinical characteristics were recorded preoperatively. Surgical outcomes, measured by objective and subjective success rates, were investigated. We evaluated the quality of life (QOL) using the Pelvic Floor Distress Inventory-20 (PFDI-20) and the Pelvic Floor Impact Questionnaire-7 (PFIQ-7). Sexual QOL was assessed by the Pelvic Organ Prolapse/Urinary Incontinence Sexual Function Questionnaire-12 (PISQ-12).Results:At postoperative 12 months, the subjective recurrence rate (7.5%) was much lower than the objective recurrence rate (40.0%). Postoperatively, no erosion was identified. One underwent a graft release procedure because of urinary retention, and one had anus sphincter reconstruction surgery due to defecation urgency. Another experienced posterior vaginal wall infection where the mesh was implanted, accompanied by severe vaginal pain. Estrogen cream relieved the pain. One patient with recurrence underwent a secondary surgery with Bard Mesh because of stage 3 anterior vaginal wall prolapse. Scoring system of PFDI-20 was from 59.150 ± 13.143 preoperatively to 8.400 ± 4.749 postoperatively and PFIQ-7 was from 73.350 ± 32.281 to 7.150 ± 3.110, while PISQ-12 was from 15.825 ± 4.050 to 12.725 ± 3.471.Conclusions:QOL and the degree of subjective satisfaction were significantly improved postoperatively. Anterior repair deserves more attention because of the higher recurrence rate. The long-term follow-up of the patient is warranted to draw firm conclusion.

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Section: Discussionmentioning

confidence: 91%

Porcine Small Intestinal Submucosa Mesh for Treatment of Pelvic Organ Prolapsed

Cao

Sun

Wang

et al. 2016

Chinese Medical Journal

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“…Synthetic meshes include non-absorbable, absorbable and composite meshes, and common complications include recurrence and infection. The recurrence rate ranges from 10 to 24% 5 while the infection rate is in the 0.5–9.0% range 6 , which has led to a bottleneck in the development of hernia surgery methods 7 – 10 . Biomaterial meshes include xenogeneic acellular dermal matrix and allogenic acellular dermal matrix meshes.…”

Section: Introductionmentioning

confidence: 99%

Polyurethane-based three-dimensional printing for biological mesh carriers

Wang,

Hou,

Shan

et al. 2024

Sci Rep

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Repair and reconstruction of the myopectineal orifice area using meshes is the mainstay of surgical treatment of inguinal hernias. However, the limitations of existing meshes are becoming increasingly evident in clinical applications; thus, the idea of using three-dimensionally (3D)-printed biological meshes was put forward. According to the current level of the 3D printing technology and the inherent characteristics of biological materials, the direct use of the 3D printing technology for making biological materials into finished products suitable for clinical applications is not yet supported, but synthetic materials can be first printed into 3D form carriers, compounded with biological materials, and finally made into finished products. The purpose of this study was to develop a technical protocol for making 3D-printed biomesh carriers using polyurethane as a raw material. In our study: raw material, polyurethane; weight, 20–30 g/m2; weaving method, hexagonal mesh; elastic tension aspect ratio, 2:1; diameters of pores, 0.1–1 mm; surface area, 8 × 12 cm2; the optimal printing layer height, temperature and velocity were 0.1 mm, 210–220 °C and 60 mm/s. Its clinical significance lies in: (1) applied to preoperative planning and design a detailed surgical plan; (2) applied to special types of surgery including patients in puberty, recurrent and compound inguinal hernias; (3) significantly improve the efficiency of doctor-patient communication; (4) it can shorten the operation and recovery period by about 1/3 and can save about 1/4 of the cost for patients; (5) the learning curve is significantly shortened, which is conducive to the cultivation of reserve talents.

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