“…A further advantage of the one‐off component of surgery relates to costs, because the costs of CPAP, estimated in the United Kingdom as £20,000 (roughly US$30,000) per quality‐adjusted life year, typically are lifelong . Main et al published a meta‐analysis of 30 randomized, cross‐over, and other controlled clinical trials, as well as certain eligible pre‐ and post‐treatment studies, specifically comparing the costs of nonsurgical (CPAP, mandibular advancement splints, and tongue‐retaining devices) versus surgical treatment of OSA . though they admitted that data were scarce, the authors estimated that, in the United Kingdom, the average cost of a UPPP procedure at the time was £1,230 to £1,550, depending on the length of hospital stay (1 vs. 2 nights) versus £220 annually for CPAP, meaning that the costs associated with CPAP would start to exceed those of surgery within 6 to 7 years.…”