Surgical Reconstruction of the Ocular Surface in Advanced Ocular Cicatricial Pemphigoid and Stevens-Johnson Syndrome

Amniotic membrane transplantation in acute chemical burns

“…It has been found useful in the treatment of persistent epithelial defect (PED) with ulceration, 16 primary, and recurrent pterygium with symblepharon, 17 for conjunctival surface reconstruction 18 and in combination with limbal grafts in the reconstruction of ocular surface in advanced ocular cicatricial pemphigoid and Steven-Johnson syndrome 19 as well as chemical and thermal burns. 20 Reports regarding the role of AMT in acute ocular burns success are highly variable.…”

Corneal sensitivity and ocular surface changes following preserved amniotic membrane transplantation for nonhealing corneal ulcers

“…Subsequently, successful applications of amniotic membrane transplantation (AMT) in cicatricial eye diseases, pterygium surgery and ocular surface reconstruction were described. [7][8][9] Amniotic membrane consists of a thick basement membrane and an avascular stroma that contains a high concentration of basic fibroblast growth factor, basement membrane components, and presumed trophic factors. The stromal matrix of the amniotic membrane is known to have the ability to exclude the inflammatory cells and promote healing.…”

Sight and comfort: complex procedures in end-stage Stevens–Johnson syndrome

“…1 Stabilising the ocular surface, reducing the severe discomfort and attempting visual rehabilitation are the major objectives, but any type of corneal graft surgery has an extremely poor prognosis in this situation. 2 We describe complex surgical techniques to rehabilitate a patient with endstage Stevens-Johnson syndrome by means of a modified Cutler-Beard-type flap, submandibular gland autotransplantation and osteo-odonto-keratoprosthesis (OOKP).…”