Surgical resection of carotid body paragangliomas: 10 years of experience

Amato, Bruno; Bianco, Tommaso; Compagna, Rita; Siano, Maria; Esposito, Giovanni; Buffone, Gianluca; Serra, Raffaele; Franciscis, Stefano de

doi:10.1016/j.amjsurg.2013.06.002

Cited by 62 publications

(68 citation statements)

References 38 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…There is a female predominance (2:1), which markedly increases when PGLs occur in high altitude societies [31,32]. The observation of bilateral and/or multifocal PGL is noted in up to 25% of carotid body PGLs and aligns with familial occurrence of predominantly SDHD mutations [33][34][35][36][37]. Aggressive behavior in the form of metastasis occurs in ~4% of cases.…”

Section: Hnpgl Sites Of Involvementmentioning

confidence: 98%

Update from the 4th Edition of the World Health Organization Classification of Head and Neck Tumours: Paragangliomas

Williams

Tischler

2017

Head and Neck Pathol

View full text Add to dashboard Cite

Section: Hnpgl Sites Of Involvementmentioning

confidence: 98%

Update from the 4th Edition of the World Health Organization Classification of Head and Neck Tumours: Paragangliomas

Williams

Tischler

2017

Head and Neck Pathol

View full text Add to dashboard Cite

“…Surgery should be performed as soon as possible at the time of diagnosis because of the growth rate potential and local invasion in patients with a long survival expectation. [9] Surgical excision is the best treatment modality for glomus caroticum tumors. Arterial continuity should be maintained and special attention should be made to avoid damaging adjacent vascular and neural structures during dissection.…”

Section: Discussionmentioning

confidence: 99%

Diagnosis and Surgical Treatment of Carotid Body Tumors

Özen¹

2015

Ann Clin Anal Med

View full text Add to dashboard Cite

ÖzetAmaç: Glomus karotikum tümörleri boyun bölgesinin nadir görülen tümörle-rindendir. Cerrrahinin esas amacı tümörün eksize edilip çıkartılmasıdır. Bu ça-lışma; ameliyat edilen hastalardaki cerrahi strateji ve cerrahi sonuçlar üzerine odaklanmıştır. Gereç ve Yöntem: Hastanemizde; 2004-2013 yılları arasında; 10 hasta (ortalama yaş 49±9; 41-69 yaş arası) karotikum tümörü tanısı ile ameliyat edilmiştir. Tanı bilgisayarlı tomografi; manyetik rezonans görüntüle-me veya Doppler ultrasonografiyi takiben yapılan dijital substraction anjiyografi ile konulmuştur. Shamblin sınıflandırmasına gore 2 hasta tip 3 ve 8 hasta da tip 2 olarak değerlendirilmiştir. Bulgular: Cerrahi sonrası mortalite gözlen-medi. Ameliyat sonrasında hastalarda nörolojik sekel görülmedi. Takip süre-si 44.11±34.62 ay(dağılım 2-98 ay) olarak saptandı. Ses kısıklığı postoperatif dönemde bir hastada meydana gelmiş olup ameliyat sonrası 2. ayda kaybolmuştur. 2 hastada preoperatif dönemde mevcut olan dilde deviyasyon ve sağ gözdeki pitozis ameliyat sonrasında da devam etti. 1 hastada ses kısık-lığı ve disfaji devam etti. 2 hasta tümör rekürensi nedeni ile tekrar ameliyat edildi. Sonuç: Glomus karotikum tümörlerinin tedavisinde en iyi yöntem cerrahidir. Arteriyal yapıların devamlılığının korunması ve cerrahi sırasında komşu vasküler ve sinir yapıların hasar görmemesi için azami dikkat gerekmektedir. Anahtar KelimelerKarotis Cisim Tümörü; Paraganglioma; Glomus Karotikum Tümörü; Karotis Arteri Abstract Aim: Carotid body tumors are rare benign tumors of the neck. Excision of the tumor is the main goal of the surgical procedure. This study is focused on the surgical strategy and results of the patients who were operated for carotid body tumor. Material and Method: 10 patients with a mean age 49±9 years; ranging from 41-69 years with carotid body tumor underwent operation in our hospital between 2004-2013. Diagnosis was made using computerized tomography; magnetic resonance imaging or digital substraction angiography after the initial doppler ultrasonography. According to Shamblin classification; 2 patients have type 3 and 8 patients have type 2 carotid body tumors. Results: There was no postoperative mortality. There were no neurologic sequelae after the operation. The follow-up period was 44.11± 34.62 months (range 2-98 months). Hoarseness developed in one patient postoperatively and it disappeared 2 months after the operation. Two patients with deviation of the tongue and pytosis of the right eyelid had the same symptoms after the operation. In one patient; hoarseness and dysphagia had continued. Reoperations were done due to recurrence of the tumor in two (20%) patients. Discussion: Surgical excision is the best treatment modality for glomus caroticum tumors. Arterial continuity should be maintained and special attention should be made to avoid damaging adjacent vascular and neural structures during dissection.

show abstract

“…Although surgery for CBT removal carries a 35% morbidity and a 1% mortality rate and a 19% risk of cranial nerve injury [5], surgical excision is the standard treatment as suggested by most of authors. The problem is surgical resection of large CBT is challenging, technically difficult and had an increasing risk of neurovascular injuries [6]. In order to avoid common postoperative neurovascular complication many suggested preoperative embolization of the feeding vessels could reduce blood loss and improve tumor excision [7,8].…”

Section: Case Reportmentioning

confidence: 99%

Clamping of external carotid artery rather than embolization during surgical removal of a huge carotid body tumor

Ali¹,

Ibrahim²,

Ali³

2015

IJCRI

View full text Add to dashboard Cite

International Journal of Case Reports and Images (IJCRI) is an international, peer reviewed, monthly, open access, online journal, publishing high-quality, articles in all areas of basic medical sciences and clinical specialties.Aim of IJCRI is to encourage the publication of new information by providing a platform for reporting of unique, unusual and rare cases which enhance understanding of disease process, its diagnosis, management and clinico-pathologic correlations. The carotid body is a gland located behind the carotid artery at the site of its bifurcation on either sides of the neck and originates from the neural crest and acts as a peripheral chemoreceptor. Case Report: A 42-year-old female presented with progressively enlarging neck swelling over five years which was associated with a recent difficulty in swallowing and hoarseness of voice. On examination there was anterolateral pulsatile neck swelling, ovoid in shape, about 6×6×7 cm in size, mobile from side to side only and firm in consistency. Computed tomography angiography (CTA) and magnetic resonance angiography (MRA) showed a mass arising at the bifurcation of common carotid artery (CCA), which has rich blood supply, splaying the external carotid artery (ECA). Blood test for vanillylmandelic acid (VMA) was negative. The patient underwent surgical excision of the tumor through an endarterectomy approach after clamping of the ECA. We report this case where clamping of ECA is being applied rather than endovascular embolization of the feeding vessels to minimize bleeding during removal of the tumor, to avoid embolization related complications and to lessen the cost of the procedure. Conclusion: Carotid body tumors are rare, however, early diagnosis and prompt treatment is essential. In a large tumor, preoperative endovascular embolization is widely used for devascularization. Clamping of the external carotid artery is a good alternative way to avoid embolization related complication with better control of bleeding, less operative time and improved cost-effectiveness.

show abstract

Surgical resection of carotid body paragangliomas: 10 years of experience

Cited by 62 publications

References 38 publications

Update from the 4th Edition of the World Health Organization Classification of Head and Neck Tumours: Paragangliomas

Update from the 4th Edition of the World Health Organization Classification of Head and Neck Tumours: Paragangliomas

Diagnosis and Surgical Treatment of Carotid Body Tumors

Clamping of external carotid artery rather than embolization during surgical removal of a huge carotid body tumor

Contact Info

Product

Resources

About