Surgical site infections following caesarean sections at Emirati teaching hospital: Incidence and implicated factors

Alnajjar, Munther S; Alashker, Dalia A.

doi:10.1038/s41598-020-75582-9

Cited by 10 publications

(8 citation statements)

References 41 publications

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“…This comes in line with previous studies that showed a single dose of cefazolin antibiotic was the most frequently administered operative antibiotic prophylaxis. 23 , 24 Additionally, these latter findings agree with the recommendation of NICE clinical guidelines (2011) regarding the best antibiotic selection and time to administer antibiotic prophylaxis. 23 , 24 The study findings encourage the importance of the clinical pharmacist in making the physicians have a better compliance to the guidelines, which shows the benefit of involving the clinical pharmacist during the stewardship program.…”

Section: Discussionsupporting

confidence: 81%

Point prevalence survey of antibiotic utilization in secondary care hospital in the United Arab Emirates

Alnajjar¹,

JAWHAR²,

ABURUZ³

et al. 2022

PHARMPRACT

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Objectives: The present study was carried out to identify and report the pattern of antibiotics prescribing to determine the adherence to the international empirical and therapeutic guidelines of antibiotic use. Methods: A point prevalence survey took place at a selected date of January 26, 2020, in which data collection was performed to all the patients present in the hospital who used at least one systemic antibiotic agent as an inpatient from 00:00 am until midnight of that day. This was performed using European Surveillance of Antimicrobial Consumption (ESAC -audit tool). The participated hospital in this point prevalence study represents a major government hospital in the UAE. Descriptive statistics were used and results were expressed using standard statistical methods. Results: Out of the 125 hospitalized patients, a total of 41 (32.8%) patients were included in the survey and treated with different trends of antibiotics on the date point prevalence survey. The total number prescribed antibiotics was 54 with a higher percentage of treatment indication (70.4%), compared to prophylaxis indication (29.6%). The combinations of penicillin's win in being the most commonly used agents by a percent of 31.5%, including the use of Amoxicillin-clavulanic acid by 22.2% and Piperacillin-tazobactam with 9.3%. The compliance with local/international guidelines accounts for 78.0% of the treated & prophylaxis patients. Conclusions: Considerable results have been obtained which can assure the quality improvement of the antibiotic use in the studied hospital.

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Section: Discussionsupporting

confidence: 81%

Point prevalence survey of antibiotic utilization in secondary care hospital in the United Arab Emirates

Alnajjar¹,

JAWHAR²,

ABURUZ³

et al. 2022

PHARMPRACT

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“…This finding is slightly in line with a study done in Nepal ( 7 ). However, the current finding is significantly higher than studies conducted at the global level ( 4 ), in China ( 5 ), India ( 6 ), and the United Arab Emirate ( 8 ). The difference may be caused by socio-economic variation, poor dietary behaviors, poor personal hygiene, inadequate infection control practices implemented in healthcare, such as limited hygienic practice, inadequate antibiotic prophylaxis, a lack of aseptic wound care, and non-adherence with prescribed treatments.…”

Section: Discussioncontrasting

confidence: 79%

“…The incidence rate of surgical site infection was 0.15% in China ( 5 ), 8.02% in India ( 6 ), and 12.6% in Nepal ( 7 ). In the United Arab Emirates, surgical site infection was detected in 1.4% of the women who underwent cesarean operations ( 8 ). According to a WHO study with a special focus on surgical site infection in low and middle-income countries, the pooled prevalence of surgical site infection was 11.2 per 100 surgical patients ( 9 ).…”

Section: Introductionmentioning

confidence: 99%

The incidence of surgical site infection and its predictors among women delivered via cesarean sections in Ethiopia: a systematic review and meta-analysis

Wondmeneh,

Mohammed

2024

Front. Med.

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BackgroundAlthough surgical wound infection remains a serious issue worldwide, the disease burden is greater in developing countries, including Ethiopia. Even though there were primary studies conducted at district levels in Ethiopia, there is little evidence about the pooled incidence of surgical site infections at the national level. Thus, this systematic review and meta-analysis determined the pooled incidence of surgical site infection and its associated factors among cesarean-delivered women in Ethiopia.MethodsWe searched PubMed, CINAHL, African Journals Online, Google Scholar, and higher educational institutional repositories. A random-effects model was used to estimate the pooled effect size with 95% confidence intervals (CIs). Funnel plot and egger tests were computed to determine the existence of publication bias. A subgroup analysis was carried out.ResultsTwenty-three studies were included in the final analysis. The pooled incidence of surgical site infection among women delivered via cesarean section was 12.32% (95% CI: 8.96–16.11%). Rural residence (AOR = 2.51, 95% CI: 1.15–3.87), membrane rupture (AOR = 2.04, 95% CI: 1.24–2.85), chorioammionitis (AOR = 4.13, 95% CI: 1.45–6.8), general anesthesia (AOR = 1.99, 95% CI: 1.22–2.75), post-operative Hgb level less than 11 mg/dL (AOR = 3.25, 95% CI: 1.54–4.96) and membrane rupture greater or equal to 12 h (AOR = 3.93, 95% CI: 1.93–5.92) were independent risk factors for surgical site infections.ConclusionMore than one in 10 women delivered via cesarean section developed surgical site infections in Ethiopia. Women living in rural areas and those with a membrane rupture, chorioammionitis, or anemia should be given special attention. General anesthesia should not be a mandatory procedure.

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“…There is a remarkable difference between the result of the current estimate of the prevalence of post‐caesarean surgical site infections in Rwanda and the prevalence of post‐caesarean SSIs in high‐income countries. For example, there was 0.4% and 5.4% post‐caesarean SSI prevalence after elective and emergency caesarean section, respectively, in Norway, 36 0.63% in Ireland, 37 1.4% in the United Arab Emirates, 38 2.7% in Canada 39 and 2.1% in Kuwait. 40 In the recent review of the global incidence of surgical site infections following caesarean section, the lowest prevalence was found in the North American region (3.87%) while the highest incidence was in the African region (11.91%).…”

Section: Discussionmentioning

confidence: 99%

Prevalence of post‐caesarean section surgical site infections in Rwanda: A systematic review and meta‐analysis

Sibomana,

Bugenimana,

Oke

et al. 2024

International Wound Journal

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Caesarean section (C‐section) is the most performed major surgery worldwide. About 15% of births are delivered through C‐section in Rwanda. The post‐caesarean surgical section is one of the most frequent complications that follow a C‐section. The purpose of this systematic review and meta‐analysis is to estimate the pooled prevalence of surgical site infections following caesarean section deliveries in Rwanda. A comprehensive search was conducted across PubMed/MEDLINE, Google Scholar, DOAJ, AJOL and the Cochrane Library to identify primary studies on post‐caesarean surgical site infections in Rwanda. Studies meeting predetermined criteria were included, and their quality was assessed using the JBI Critical Appraisal Tools. Heterogeneity was evaluated using I2 statistics, while publication bias was examined via funnel plots and statistical tests. Pooled prevalence was calculated using Jamovi 2.3.28 software, with subgroup analysis conducted to identify sources of heterogeneity. Statistical significance was set at p < 0.05. From 139 articles initially searched from the databases, only 17 studies with 8, 082 individuals were finally included in the systematic review and meta‐analysis. Using the random‐effects model, the pooled estimate of post C‐section SSIs prevalence in Rwanda was 6.85% (95% CI 5.2, 8.5). Subgroup analysis based on publication year, sample size, hospital and study design showed no much difference in SSI prevalence. The current systematic review and meta‐analysis indicates that post‐caesarean surgical site infections are significant in Rwanda. A collaborative effort is required to lower post‐C‐section SSIs and provide the best surgical care in the country.

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Surgical site infections following caesarean sections at Emirati teaching hospital: Incidence and implicated factors

Cited by 10 publications

References 41 publications

Point prevalence survey of antibiotic utilization in secondary care hospital in the United Arab Emirates

Point prevalence survey of antibiotic utilization in secondary care hospital in the United Arab Emirates

The incidence of surgical site infection and its predictors among women delivered via cesarean sections in Ethiopia: a systematic review and meta-analysis

Prevalence of post‐caesarean section surgical site infections in Rwanda: A systematic review and meta‐analysis

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