Objectives: Consensus regarding initial cannulation site for acute type A dissection repair is lacking. Objectives were to review our experience with systematic initial axillary artery cannulation, characterize patients on the basis of cannulation site, and assess outcomes.Methods: From January 2000 to January 2017, 775 patients underwent emergency acute type A dissection repair. Initial axillary cannulation was performed in 617 (80%), femoral in 93 (12%), and central in 65 (8.4%). In-hospital mortality and stroke risk factors were identified using logistic regression.
Results:Reasons for selecting initial central or femoral instead of axillary cannulation included unsuitable axillary anatomy (n ¼ 67; 42%), surgeon preference (n ¼ 38; 24%), hemodynamic instability (n ¼ 34; 22%), and preexisting cannulation (n ¼ 19; 12%). Cannulation site was shifted or added intraoperatively in 82 (11%), with initial cannulation site being axillary (n ¼ 23 of 617; 3.7%), central (6 of 65; 9.2%), or femoral (n ¼ 53 of 93; 57%), for surgeon preference (n ¼ 60; 73%), high flow resistance (n ¼ 13; 16%), increased aortic false lumen flow (n ¼ 6; 7.3%), and other (n ¼ 3; 3.7%). In-hospital mortality was 8.6% (n ¼ 67; lowest for axillary, 7.3% [P ¼ .02]) and stroke 8.3% (n ¼ 64). Hemodynamic instability (odds ratio [OR], 7.