Surgical Therapy of Ascending Thrombophlebitis in the Saphenous System

Superficial Vein Thrombosis

“…Surgery, including thrombectomy, vein stripping, vein ligation, and sclerotherapy, has also been suggested for treatment of SVT [ 7,9,26,29,35,[39][40][41][42] . Surgery may be as effective as anticoagulation when a thrombus is found in the SPJ or SFJ and extends as free fl oating in the CFV or popliteal veins [ 7 ] .…”

“…Disadvantages of surgery are that it is invasive and there is a risk of PE when performed early [ 43 ] . Stripping and sclerotherapy can increase the risk of PE [ 44,45 ] , with symptomatic PE reported in up to 8% of patients following stripping [ 42 ] . In addition, in a recent study where surgery and LMWH were compared, the incidence of PE was 6.7% with surgery and 0% with LMWH ( P = ns).…”

A Pilot Randomized Double-blind Comparison of a Low-Molecular-Weight Heparin, a Nonsteroidal Anti-inflammatory Agent, and Placebo in the Treatment of Superficial Vein Thrombosis

“…Indeed, the 4.5% incidence of deep venous thromboembolism in the placebo group at 3 months falls within the range reported in previous smaller open studies. [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15] This 4.5% incidence is probably underestimated because patients with associated deep vein thrombosis or pulmonary embolism at enrollment were excluded, a situation found in 120 (13.8%) of the 867 patients screened, as shown by the analysis of the study log. Moreover, most patients with venous thromboembolism by day 12, whether symptomatic or not, received curative doses of anticoagulant therapy, which could have prevented the occurrence of symptomatic deep venous thromboembolism during fol-low-up.…”

“…2003;163:1657-1663 S UPERFICIAL VEIN thrombosis of the lower limbs is a common disease, usually considered benign. However, studies [1][2][3][4][5][6][7][8][9][10][11][12][13] suggest that the frequency of association between superficial and deep vein thromboses ranges from 3% to 40%. Furthermore, pulmonary embolism has been clinically suspected to occur in 2% to 13% of patients with superficial vein thrombosis 2,3,8,14 and in 20% to 33% of patients when it has been checked by lung scanning.…”

“…When superficial vein thrombosis occurs alone, treatment is generally ambulatory; various therapies have been proposed, such as active ambulation, graduated compression stockings, nonsteroidal antiinflammatory agents, antithrombotic therapy, and, in selected cases, surgical intervention. [1][2][3]13,[17][18][19][20][21][22] However, none of these treatments has been evaluated in adequately designed trials.…”