2017
DOI: 10.14503/thij-16-5772
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Surgical Treatment of Constrictive Pericarditis

Abstract: T he normal pericardium consists of 2 layers: a fibrous outer layer and a serous inner layer. The pericardial space is enclosed within these 2 layers and normally contains 20 to 50 mL of serous fluid. The pericardium serves a variety of functions. In addition to its mechanical effects on the heart (limiting distention, promoting chamber-coupling interaction, maintaining cardiac geometry, enabling frictionless movement, and serving as a barrier to infection), the pericardium has immunologic, vasomotor, paracrin… Show more

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Cited by 69 publications
(93 citation statements)
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“…Complete pericardiectomy has been proven to be not only associated with lower perioperative mortality [9] but also confer significant long-term survival benefit and clinical functional improvement [10,18] . Generally, pericardiectomy can be performed through either median sternotomy or left anterolateral thoracotomy, while median sternotomy provides adequate exposure of the right atrium, right ventricle and the vena cava, thus enabling extensive pericardial resection [19] .…”
Section: Discussionmentioning
confidence: 99%
“…Complete pericardiectomy has been proven to be not only associated with lower perioperative mortality [9] but also confer significant long-term survival benefit and clinical functional improvement [10,18] . Generally, pericardiectomy can be performed through either median sternotomy or left anterolateral thoracotomy, while median sternotomy provides adequate exposure of the right atrium, right ventricle and the vena cava, thus enabling extensive pericardial resection [19] .…”
Section: Discussionmentioning
confidence: 99%
“…Constrictive pericarditis is a progressive course which is associated with pericardial fibrosis with or without calcification and incomplete ventricular filling, which causes congestion and reduces cardiac output. 15,16 One of the most common causes of constrictive pericarditis is the history of previous cardiac surgery. After pericardiotomy, temporary loss of pericardial elasticity results in formation of pericardial effusion, fibrin deposition, and inflammation.…”
Section: Discussionmentioning
confidence: 99%
“…After pericardiotomy, temporary loss of pericardial elasticity results in formation of pericardial effusion, fibrin deposition, and inflammation. 16 Generally, constrictive physiology will develop between 5 and 30 days after the surgery. 4 In most patients, pericardial effusion will be absorbed and inflammation will be reduced; but in some patients, pericardial inflammation persists and leads to pericardial fibrosis and calcification, which becomes constrictive pericarditis.…”
Section: Discussionmentioning
confidence: 99%
“…Surgical treatment includes drainage of pericardial fluid in effusive pericarditis and removal of thickened pericardium from the surface of the heart and the great vessels including the aorta, pulmonary artery and the vena cavas 21 . Pericardiectomy is defined as the removal of a portion or all of the pericardium, this procedure is commonly indicated for constrictive pericarditis 22 .…”
Section: Introductionmentioning
confidence: 99%