Surgical treatment of esophageal perforation after stereotactic body radiotherapy: A report of two cases

Kato, Takumi; Kazama, Yusuke; Matsuura, Sho; Nagaoka, Sakae

doi:10.1016/j.ijscr.2022.107805

Cited by 1 publication

(2 citation statements)

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“…Among nine cases, three cases were treated with chemoradiotherapy and two cases were treated with vascular endothelial growth factor inhibitor (bevacizumab). Necrosis induced by radiotherapy or delayed wound healing by bevacizumab treatment have been reported as the risk factors for fistula formation in gastrointestinal cancers 15–17 . The duration from the initial treatment of tumors to fistula formation varied from 2 weeks to 3 months.…”

Section: Discussionmentioning

confidence: 99%

“…Necrosis induced by radiotherapy or delayed wound healing by bevacizumab treatment have been reported as the risk factors for fistula formation in gastrointestinal cancers. 15 , 16 , 17 The duration from the initial treatment of tumors to fistula formation varied from 2 weeks to 3 months. Intriguingly, seven out of nine cases developed fistula on the anterior or lateral wall of the trachea with better prognosis, while fistulas located on the posterior walls of mainstem bronchus were associated with a poor prognosis.…”

Section: Discussionmentioning

confidence: 99%

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Tracheomediastinal fistula induced by concurrent chemoradiotherapy in small cell lung cancer: A case report and literature review

Yamamoto,

Shibahara,

Mori

et al. 2024

Thoracic Cancer

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Tracheomediastinal fistula is a rare but life‐threatening complication of cancer. We report a case of tracheomediastinal fistula induced by concurrent chemoradiotherapy in limited stage small cell lung cancer. Despite the treatment response, the metastatic paratracheal lymph node increased gradually during concurrent chemoradiotherapy, resulting in the occurrence of tracheomediastinal fistula and mediastinitis. Without any surgical intervention, the patient achieved successful recovery from mediastinitis through antibiotic treatment, although the tracheomediastinal fistula remained open. In this report, we also review previous studies of tracheomediastinal and bronchomediastinal fistulas and summarize the clinical features.

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Section: Discussionmentioning

confidence: 99%