Surgical treatment of gastrointestinal carcinomas in octogenarians: risk factors for complications and long-term outcome

Influence of Comorbidity and Age on 1-, 2-, and 3-Month Postoperative Mortality Rates in Gastrointestinal Cancer Patients

“…30,31 A previous study has shown that cardiac complications are the most common complications in octogenarians after surgery for GI cancer. 32 In addition, cardiac complications occur more often among (colon) cancer patients with cardiovascular disease compared to those without comorbidities. 14 In our study population, comorbidity affected postoperative mortality for all tumor sites, but specifically for patients with esophageal cancer.…”

Improving the outcomes in gastric cancer surgery

“…But as far as the authors are aware no literature on this subject exists to date. Other objective parameters such as lowered preoperative serum albumin levels have been identified as risk factors for postoperative complications after surgery for gastrointestinal carcinomas [35,36] . But the latter risk factors remain under debate as some authors dispute the role of malnutrition and lowered serum albumin levels as risk factors for impaired outcome after gastric cancer surgery [37] .…”

Lymphadenectomy: state of the art

“…These data indicate that extended lymphadenectomy can be performed safely in Western patients when adopting correct criteria and with an adequate surgical volume. Anyway, some risk factors for morbidity, linked to patient characteristics, have been identified in different studies: advanced age (particularly after 75 years), presence of important comorbidities (mainly cirrhosis and renal failure), high comorbidity index, hypoalbuminemia and poor nutritional status are those more frequently associated with advanced grade of postoperative complications after gastrectomy with lymphadenectomy (42,(44)(45)(46)(47). A characteristic of specialized centers is the ability to prompt identification and management of severe complications, which is associated with a significant decrease of their lethality rate.…”