2021
DOI: 10.1016/j.jseint.2021.01.011
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Surgical treatment of humeral head avascular necrosis in patients with sickle cell disease: a systematic review

Abstract: Background Sickle cell disease is the leading etiology for atraumatic humeral head avascular necrosis worldwide. Treatment of this condition is not standardized, with only few studies evaluating clinical outcomes after surgical interventions. The aim of this study was to review the available evidence on the results of surgical intervention for humeral head avascular necrosis in the sickle cell disease population. Methods A systematic electronic search was conducted usin… Show more

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Cited by 6 publications
(2 citation statements)
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“…However, according to the information that is currently available, it has not been proven to stop or slow the usual development and progression of the disease. Despite the fact that shoulder arthroplasty typically has good outcomes in its later stages, data on long-term implant survival and issues are scarce [ 14 , 15 ].…”
Section: Discussionmentioning
confidence: 99%
“…However, according to the information that is currently available, it has not been proven to stop or slow the usual development and progression of the disease. Despite the fact that shoulder arthroplasty typically has good outcomes in its later stages, data on long-term implant survival and issues are scarce [ 14 , 15 ].…”
Section: Discussionmentioning
confidence: 99%
“…Large humeral head chondral lesions have been shown to result from a number of etiologies including trauma, previous surgery, avascular necrosis (AVN), osteoarthritis, or idiopathic chondrolysis. [1][2][3] Such lesions, which are typically located on the humeral head, are difficult to diagnose via preoperative clinical examination and imaging techniques and are often discovered during arthroscopy. 1,4 Although joint-preservation techniques are sometimes indicated in young patients without arthritis, shoulder arthroplasty traditionally has been the treatment of choice to treat isolated, large chondral defects of the humeral head in older patients.…”
mentioning
confidence: 99%