Surgical Treatment of Intraductal Papillary Neoplasm of the Bile Duct: A Report of Two Cases and Review of the Literature

Abstract

Intraductal papillary neoplasm of the bile duct (IPNB) is a rare bile duct tumor characterized by intraductal papillary or villous neoplasms covered by neoplastic epithelium with fine fibrovascular stalks in the dilated bile ducts (1). Its true etiology remains unknown. Herein, we report two cases of IPNB that underwent surgical resection. The first case was a 66-year-old male who complained of upper abdominal pain for three years. We found obstruction of the common bile duct and dilation of the intrahepatic and extrahepatic bile ducts after MRCP. Laparoscopic hepatic segmentectomy (S2, S3, S4), resection of the common bile duct, cholecystectomy, and hepaticojejunostomy were performed. The second case was a 67-year-old male with asymptomatic dilation of the intrahepatic duct. The patient underwent robot-assisted laparoscopic hepatic segmentectomy (S5, S6, S7, S8), resection of the common bile duct, hepaticojejunostomy and cholecystectomy.

Intraductal papillary neoplasm of the bile duct: A case report of a rare tumor with a brief review of literature

“…The common radiologic findings for IPNB are bile duct dilatation, intraductal mass and cystic lesion [ 23 ]. Both upstream and downstream dilatation of bile duct is common in mucin overproduction type of IPNB.…”

Robotic hepatectomy and cholecystectomy in the management of intraductal papillary mucinous neoplasm of the biliary tract: A case report and literature review

“…IPMN is characterised by the formation of abnormal growths or tumours within the bile ducts. [1][2][3][4] These growths can lead to obstruction of the bile ducts, which can cause symptoms such as jaundice, additional imaging examinations were also performed in many patients. In all cases, the bile duct was dilated, similar to the ultrasound presentation in this case.…”

“…IPMN is a rare condition that can affect the bile ducts of the liver. IPMN is characterised by the formation of abnormal growths or tumours within the bile ducts 1–4 . These growths can lead to obstruction of the bile ducts, which can cause symptoms such as jaundice, abdominal pain, and abnormal liver function tests.…”

“…Surgical treatment for IPMN of the bile ducts of the liver can involve two main approaches: bile duct resection and liver transplantation 1–4 . Bile duct resection, also known as hepaticojejunostomy or hepaticoduodenostomy, focuses on removing the diseased portion of the bile duct and creating a new connection between the remaining healthy bile duct and the small intestine.…”

“…CT scans use X-rays and computer processing to generate cross-sectional images, enabling the detection of struc- Surgical treatment for IPMN of the bile ducts of the liver can involve two main approaches: bile duct resection and liver transplantation. [1][2][3][4] Bile duct resection, also known as hepaticojejunostomy or hepaticoduodenostomy, focuses on removing the diseased portion of the bile duct and creating a new connection between the remaining healthy bile duct and the small intestine. This procedure is performed through an abdominal incision, where the surgeon carefully removes the affected segment of the bile duct, including any associated tumours or growths.…”