Surgical Treatment of Multiple Hydatid Cysts in the Liver of a Pediatric Patient

Lv, Hailong; Jiang, Yufeng; Liu, Guisheng; Zhang, Shijie; Peng, Xinyu

doi:10.4269/ajtmh.14-0445

Cited by 7 publications

(6 citation statements)

References 15 publications

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“…In this study, eosinophil count was normal before the surgery, but it increased prominently after the surgery. A reason for this could be that some rupture occurred during surgical removal of the hydatid cysts [ 27 ]. Also, the increase in eosinophilia may be due to drug treatment 4 weeks before surgery, which is similar to the report of Di Comite et al who stated eosinophilia increased from 30% to 48% after treatment [ 28 ].…”

Section: Discussionmentioning

confidence: 99%

Cystic Echinococcosis/Hydatid Cyst Coinfection with HIV: A Report from Shiraz, Iran

Sharifi

Sadjjadi

Nikoupour

et al. 2021

Canadian Journal of Gastroenterology and Hepatology

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HIV coinfected with other parasitic diseases may cause a serious problem for the patients. A few case reports describing echinococcosis with human immunodeficiency virus (HIV) infection have been reported in the world; however, it has not been reported in Iran, so far. Here, the first case of liver hydatid cyst coinfected with HIV in Iran is reported. The patient is a 46-year-old female HIV-positive based on the laboratory report. Her clinical symptoms included abdominal pain, abdominal enlargement, and anorexia. Ultrasound showed three large hepatic hydatid cysts with hundreds of daughter cysts. Ultrasonography of the cyst revealed it as a CE2 stage according to the WHO classification. The patient went under complete anesthesia followed by complete cyst removal by surgery. Observation of the hydatid cyst fluid using eosin 0.1% revealed more than 70% viable protoscoleces. Histopathology examination, polymerase chain reaction (PCR), and viable protoscoleces confirmed the diagnosis of echinococcosis. The IgG ELISA test with native AgB for E. granulosus infection was also positive. mtDNA amplification using PCR and sequencing showed the cyst as E. granulosus sensu stricto genotype. Our observations show that huge, large, and high-pressure cysts with hundreds of daughter cysts are difficult to be completely removed, and drug treatment has not been able to reduce their size. Therefore, in HIV coinfection with hydatid cyst, surgery is preferable to other treatments.

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Section: Discussionmentioning

confidence: 99%

Cystic Echinococcosis/Hydatid Cyst Coinfection with HIV: A Report from Shiraz, Iran

Sharifi

Sadjjadi

Nikoupour

et al. 2021

Canadian Journal of Gastroenterology and Hepatology

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“…Echinococcosis is a parasitic disease caused by the E. granulosus parasite's larva stage in intermediate hosts, including humans and other warm-blooded vertebrates. Morphologically, the disease can be recognized as multiple hydatid cysts within different internal organs of infected host particularly in the liver (1). The disease represents a real global challenge against health and economic development, especially in the third world states, due to lack of critical health care in humans and dogs, as well as large numbers of wild dogs that live near to the human communities which increase the infection risk.…”

Section: Introductionmentioning

confidence: 99%

Perturbation of liver function markers and serum electrolytes associated with Echinococcus granulosus infection in sheep

Ali¹,

Jihad²

2022

IJVS

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Histopathological alterations in the liver of intermediated hosts infected with Echinococcus granulosus parasite can be occurred by necrotic expansion as a result of an increase in growth of the parasite larva stage (metacestode), which may cause perturbation in production of liver function markers. Thus, this study aims to determinate the liver biochemical profile and some serum electrolytes of E. granulosus-infected sheep at different hydatid cyst infection ratios (IRs). fifty livers from naturally E. granulosusinfected sheep with five livers from uninfected-sheep as a control group were enrolled in this study. Cardiac blood samples under sterilized conditions were gently collected and isolated sera were biochemically assayed for determination of liver function markers including; Aspartate transaminase (AST), Alanine transaminase (ALT), alkaline phosphatase (ALP), Albumin (ALB) and total protein (TP), as well as the level of some serum electrolytes including Ca, K, Na and Cl using fully automatic biochemical analyzer, FUJI-Film. The current data indicated a progressive increase in the level of AST, ALT, ALP, Ca and K. The level of ALB and TP were gradually declined with a rise of liver infection ratio with hydatid cysts. In conclusion, the current findings indicated perturbation of liver function markers and the level of some serum electrolytes, mainly Ca and K in E. granulosus-infected sheep based on the infection ratio of liver. Additionally, acute and chronic infection of E. granulosus parasites in sheep can be determined based on the level of liver function markers in serum.

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“…24 In most cases eosinophilia is mild (< 15%) or absent but may increase prominently post-surgery. 26 Eosinophilia was present in three of nine patients and increased in three patients post-manipulation.…”

Section: Discussionmentioning

confidence: 85%

Case Series of Cystic Echinococcosis Over a Twelve-year Period at Sultan Qaboos University Hospital, Oman

Hassan¹,

Balushi²,

Kumar³

et al. 2023

Oman Med J

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Objectives: Cystic echinococcosis is a worldwide zoonosis that is endemic in many countries including some in the Middle East. Exact prevalence rates for human echinococcosis are unknown for Oman. Methods: Following obtaining ethical approval, data from January 2010 to December 2021 were retrieved from hospital electronic records of Sultan Qaboos University Hospital, Muscat. Results: Over a 12-year period we saw nine cases of hydatid disease; two cases in females and seven cases in males. The median age of our patients was 31 years old. Four patients had pulmonary cysts, four had hepatic cysts, and one patient had pulmonary and hepatic cysts. The majority of patients were from the Ad Dakhiliyah governorate. Contact with animals was reported by three patients, denied by two, and unknown for four. Albendazole was prescribed to three patients with pulmonary cysts that subsequently ruptured reflecting the unfamiliarity of clinicians to best manage pulmonary hydatid cysts. Conclusions: The prevalence of cystic echinococcosis in Oman is unknown but appears rare. For optimal management of this disease, clinicians must become more aware of its diagnosis and management.

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Surgical Treatment of Multiple Hydatid Cysts in the Liver of a Pediatric Patient

Cited by 7 publications

References 15 publications

Cystic Echinococcosis/Hydatid Cyst Coinfection with HIV: A Report from Shiraz, Iran

Cystic Echinococcosis/Hydatid Cyst Coinfection with HIV: A Report from Shiraz, Iran

Perturbation of liver function markers and serum electrolytes associated with Echinococcus granulosus infection in sheep

Case Series of Cystic Echinococcosis Over a Twelve-year Period at Sultan Qaboos University Hospital, Oman

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