Surgical Treatment of Nail Apparatus Melanoma in situ: The Use of Artificial Dermis in Reconstruction

Hayashi, Kôichi; Uhara, Hisashi; Koga, Hiroshi; Okuyama, Ryuhei; Saida, Toshiaki

doi:10.1111/j.1524-4725.2011.02217.x

Cited by 13 publications

(13 citation statements)

References 9 publications

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“…This approach has been confirmed in a large comparative study of 62 patients (78). More and more centers have now adopted a functional approach for the surgery of early ungual melanoma (54,(79)(80)(81)(82)(83)(84). In their series of 31 subungual melanomas treated with wide local excision and another 31 ungual melanomas treated by amputation, the 5-year survival rates were 92% vs. 66.5%, respectively.…”

Section: Treatmentmentioning

confidence: 99%

Ungual melanoma - controversies in diagnosis and treatment

Haneke

2012

Dermatol Ther

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Ungual melanomas are considered rare, being difficult to diagnose, and having a poor prognosis. The aim of the present study was to discuss the epidemiology, potential causes, treatment options, and outcome of ungual melanomas. In contrast to assumptions in many articles, ungual melanomas are not rare when calculated for the cumulative size of the nail apparatus of both the fingers and toes. The prognosis is not worse than that of melanomas with the same thickness, mitotic rate, or presence of ulceration on other sites. Melanomas of the nail apparatus behave similar to melanomas in other localizations. What makes them enigmatic is the high rate of misdiagnoses and very late diagnoses.

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Section: Treatmentmentioning

confidence: 99%

Ungual melanoma - controversies in diagnosis and treatment

Haneke

2012

Dermatol Ther

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“…However, in this scenario, reconstruction after wide local excision can be associated with functional loss or chronic pain. In such cases, dermal matrix plays an important role as it provides satisfactory aesthetic and functional outcomes [12]. In both cases, amputation could be avoided and the patients report good quality of life after surgery.…”

Section: Discussionmentioning

confidence: 99%

“…More recently, Matriderm and Integra use in oncology and reconstructive surgery has also been reported [10–12]. These reports show no difference in oncological outcomes and are technically feasible.…”

Section: Introductionmentioning

confidence: 99%

Dermal Substitutes Use in Reconstructive Surgery for Skin Tumors: A Single-Center Experience

Campagnari

Jafelicci

Carneiro

et al. 2017

International Journal of Surgical Oncology

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Reconstructive surgery following skin tumor resection can be challenging. Treatment options after removing the tumor are skin grafting, local pedicled and axial flaps, or microsurgery for complex and extensive wounds correction. Recently, the use of dermal substitutes has been extended to reconstructive surgery in cutaneous oncology. Objectives. To report both a single-center experience using dermal substitutes in reconstructive surgery for skin malignancies and reconstructive surgery's outcomes. Methods and Results. Among thirteen patients, seven (53.8%) were male with mean age of 62.6 years. Regarding diagnosis, there were five cases (38.5%) of basal cell carcinoma (BCC), two (15.4%) of melanoma in situ, two (15.4%) of dermatofibrosarcoma protuberans, one (7.7%) of squamous cell carcinoma (SCC), one (7.7%) of angiosarcoma, and one (7.7%) of eccrine carcinoma (EC). The most common site of injury was scalp (53.8%) and lower limbs (23.1%). Seven (53.8%) patients used NPWT and six (46.2%) patients underwent Brown's dressing. The most frequent complication of the first stage was wound contamination (38.5%). Average time to second-stage skin grafting was 43.9 days. Three (23%) patients developed tumor recurrence and one died. Conclusions. Use of dermal substitutes in oncology can be an option for reconstruction after extended resections, providing good aesthetical and functional results.

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“…3), which is defined as a Breslow tumor thickness (TT) ≤0.5 mm [33][34][35][36][37][38]. There have also been a few case reports of two-step surgeries using artificial dermis tissue for the tentative coverage of the defect after local excision, followed by skin graft coverage after the histopathological confirmation of negative surgical margins [39,40]. These strategies are becoming more common, although the total number of such surgeries still remains small.…”

Section: In Situ or Minimally-invasive Summentioning

confidence: 99%