2013
DOI: 10.1097/aln.0b013e31829c2f22
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Surgical Treatment of Permanent Diaphragm Paralysis after Interscalene Nerve Block for Shoulder Surgery

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Cited by 51 publications
(36 citation statements)
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“…Inflammatory mechanisms have recently been proposed as the cause for persistent phrenic nerve injury following interscalene block for shoulder surgery. Kaufman and colleagues 46 reported a series of 14 patients with chronic diaphragmatic paralysis following interscalene block. During surgical exploration, adhesions, fascial thickening, vascular changes, and scar tissue (present in 10 of 14 patients) involving the phrenic nerve suggested chronic inflammation and were consistent with a compression neuropathy.…”
Section: Inflammatory Injurymentioning
confidence: 99%
See 1 more Smart Citation
“…Inflammatory mechanisms have recently been proposed as the cause for persistent phrenic nerve injury following interscalene block for shoulder surgery. Kaufman and colleagues 46 reported a series of 14 patients with chronic diaphragmatic paralysis following interscalene block. During surgical exploration, adhesions, fascial thickening, vascular changes, and scar tissue (present in 10 of 14 patients) involving the phrenic nerve suggested chronic inflammation and were consistent with a compression neuropathy.…”
Section: Inflammatory Injurymentioning
confidence: 99%
“…52 However, surgical literature warns that the risk of block-related PNI may be higher than that reported in anesthesia literature. 46,[53][54][55] In the following section, we discuss several technical, equipment, and anatomical factors that may influence the risk of nerve injury.…”
Section: Anesthetic Factorsmentioning
confidence: 99%
“…[5] Although HDP is usually transient, rare cases of prolonged or persistent HDP after single-injection or continuous ISB have been reported. [68] The incidence of persistent HDP following ISB for shoulder surgery is of 1 per 2069 (0.048%). [9] …”
Section: Discussionmentioning
confidence: 99%
“…[11] A recent study suggested that inflammation played a significant role in the mechanism of persistent HDP. [8] The study reported intraoperative findings of adhesions, fascial thickening, and vascular changes secondary to inflammation during phrenic nerve surgery. However, although inflammation might play a crucial role in the mechanism of nerve injuries, it is unclear whether this results from the catheter or from other factors.…”
Section: Discussionmentioning
confidence: 99%
“…This is associated with significant side effects including phrenic nerve paralysis approaching 100 %, especially with traditional, high volume blocks [47]. Permanent phrenic nerve dysfunction is rare but can be a devastating injury impeding respiratory function [48]. Supraclavicular brachial plexus blocks are a reasonable analgesic alternative and carry slightly less risk of diaphragm paraesis.…”
Section: Upper Limb Surgerymentioning
confidence: 99%