Surgical Treatment of Peyronie's Disease: A Single Center Experience with 145 Patients

Kadıoğlu, Ateş; Şanlı, Öner; Akman, Tolga; Çakan, Murat; Erol, Bülent; Mamadov, Firdovsi

doi:10.1016/j.eururo.2007.04.045

Cited by 78 publications

(55 citation statements)

References 26 publications

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“…The advantages presented to support this use were several (32)(33)(34)(35). As reported in Table 3, overall success rates for straightening of the penis with the use of saphenous vein grafting ranged between 66.6% and 96% (36)(37)(38)(39)(40)(41)(42)(43)(44)(45). Despite promising theoretical properties, saphenous vein grafting clinical results are not so satisfactory.…”

Section: Results Of Buccal Mucosa (Bm) Grafting Vs Saphenous Vein (Svmentioning

confidence: 99%

“…In addition, the patient satisfaction rate in the short term ranged from 88% to 100% but it tends to decrease to 60-86% in the few series with a follow-up longer than 5 years (38). The major drawback of venous graft was the need for a second incision to harvest the vein, then the bulging of the graft, indentations or hourglass deformities, sensory loss and persistent pain (36). Compared with the others graft material, characteristics of buccal mucosa are more favorable, also considering the functional and cosmetic results as reported in our experience and in literature ( Table 4 and related references in Supplementary Materials posted in www.aiua.it).…”

Section: Results Of Buccal Mucosa (Bm) Grafting Vs Saphenous Vein (Svmentioning

confidence: 99%

See 1 more Smart Citation

Buccal mucosa is a promising graft in Peyronie’s disease surgery. Our experience and a brief literature review on autologous grafting materials

Fabiani

Servi

Fioretti

et al. 2016

Arch Ital Urol Androl

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Section: Results Of Buccal Mucosa (Bm) Grafting Vs Saphenous Vein (Svmentioning

confidence: 99%

Section: Results Of Buccal Mucosa (Bm) Grafting Vs Saphenous Vein (Svmentioning

confidence: 99%

Buccal mucosa is a promising graft in Peyronie’s disease surgery. Our experience and a brief literature review on autologous grafting materials

Fabiani

Servi

Fioretti

et al. 2016

Arch Ital Urol Androl

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show abstract

“…[16][17][18] Patients undergoing tunical lengthening procedures had a less favourable outcome with only 46% being able to achieve satisfactory penetrative function. A recent study by Kadioglu et al 19 reported such success in over 75% of patients undergoing autologous saphenous vein interposition grafting. In a review of published studies, tunical lengthening and autologous saphenous vein grafting had postoperative erectile dysfunction ranging from 0 to 46%.…”

Section: Discussionmentioning

confidence: 96%

“…Management and patient selection for penile prosthesis operations was similar in other series, where patients were offered penile prostheses as first line management of Peyronies disease with concomitant erectile dysfunction resistant to therapy. 6,19,22 There are numerous studies comparing the efficacies of various surgical techniques for the treatment of Peyronie's disease. Postoperative outcomes vary greatly with factors such as surgical competency and the quality of pre and postoperative care being largely responsible for such large discrepancies in result.…”

Section: Discussionmentioning

confidence: 99%

Should assessment of penetrative sexual activity be used as the treatment arbiter in the management of Peyronie's disease?

et al. 2011

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Peyronie's disease is an inflammatory disorder, which causes thickening of the tunica albuginea of the penis. Peyronie's disease has a variable natural history and the assessment and management of the disease has yet to be standardised. The case notes of 97 patients with a diagnosis of Peyronie's disease were retrospectively reviewed at a single tertiary referral centre. Patients who were able to achieve sexual penetrative activity to the satisfaction of both partners were managed conservatively. Patients who were unable to achieve penetrative sexual activity were given intra-cavernosal prostaglandin, with those achieving a satisfactory erection being offered appropriate surgical intervention. The mean age at presentation was 50 years (range 18-82). A total of 59 (61%) men were able to have penetrative sex at the time of presentation. Following initial conservative management, only five (8%) of this group had disease progression, which stopped them from being able to penetrate. In all 38 (39%) men who were not able to penetrate at presentation were offered surgical intervention. In all 24 (63%) of these men chose to have surgical intervention. Tunical plication resulted in the ability to penetrate in 77% of men choosing this option whereas only 46% of men undergoing autologous saphenous vein grafting were able to have penetrative sex. Assessment of penetrative sexual function is an essential component of the management of patients with Peyronie's disease. This enables appropriate counselling with respect to possible conservative management or the most appropriate surgical intervention. The majority of patients with Peyronie's disease can achieve sexual penetrative activity, many without surgical intervention.

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“…6 The above procedures are less useful in cases of severe curvature (greater than 601) because they cause penile shortening and can induce palpable bulges under the skin. 3,7,[8][9][10] Currently, the reference technique for severe curvature is plaque incision followed by grafting. 5,11 Plaque excision is no longer used because of the high rates of recurrence and de novo ED.…”

Section: Introductionmentioning

confidence: 99%

Medium-term follow-up of plaque incision and porcine small intestinal submucosal grafting for Peyronie's disease

et al. 2010

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The best surgical option for the management of severe cases of Peyronie's disease is currently a matter of debate. To determine medium-term outcomes and complications after treatment of severe Peyronie's disease by porcine small intestinal submucosa (SIS) grafts, we retrospectively reviewed 33 consecutive plaque incisions followed by 4-ply SIS grafting in 28 patients (2002)(2003)(2004)(2005)(2006)(2007)(2008)(2009). Postoperative complications, penile length preservation, de novo ED, penile curvature correction and curvature recurrence rates were recorded. Median patient age was 54 years (38-69 years). Median preoperative curvature was 901 (30-901) (stable for at least 6 months). Six patients (21%) had preoperative ED. There were few postoperative complications (no cases of infection, haematoma (n ¼ 2), penile hypoesthesia (n ¼ 1), patch rejection and migration (n ¼ 1)). Subjective penile shortening and de novo ED were observed in 7 (25%) and 3 (11%) patients, respectively. The success rate for the procedure (straight penis or curvature p201 and ability to have intercourse) was 67% (22/33). Four patients achieved curvature correction after a repeat procedure with a new SIS graft. Eleven patients experienced recurrence within 3 months of surgery. After a median follow-up of 9 months (3-94), 22 patients (79%) had a satisfactory curvature correction.

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Surgical Treatment of Peyronie's Disease: A Single Center Experience with 145 Patients

Cited by 78 publications

References 26 publications

Buccal mucosa is a promising graft in Peyronie’s disease surgery. Our experience and a brief literature review on autologous grafting materials

Buccal mucosa is a promising graft in Peyronie’s disease surgery. Our experience and a brief literature review on autologous grafting materials

Should assessment of penetrative sexual activity be used as the treatment arbiter in the management of Peyronie's disease?

Medium-term follow-up of plaque incision and porcine small intestinal submucosal grafting for Peyronie's disease

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