Surgical treatment results of purulent corneal ulcers in HIV patients

Abstract

Purulent corneal ulcers – severe inflammatory disease, often with unfavourable outcome. Therapeutic keratoplasty of this disease is the main treatment way. The total number of HIV cases in Russia and throughout the world is permanently increasing. 75 % of HIV-infected have ophthalmology manifestations, among all of them only 5 % is infection corneal lesions. The information about patients initial immune status could contribute to the successful surgical results. Results of surgical treatment of corneal ulcer in HIV-patients was analysed. Period of operations was from 2018 to 2022 years and the clinical base was Kemerovo Regional Clinical Ophthalmological Hospital. Among patients were 2 females and 4 males, the age was from 36 to 72 years old. Penetrating keratoplasty for emergency reasons with tectonic or organ preservation aims was made for all of them. Retrospective analysis showed that transparent engraftment of the transplant was better after the only operation. The secondary keratoplasty was needed in 50 % cases. Corneal leucoma after the keratoplasty and the previous infection was in patients with 10 years HIV-infection in the anamnesis regardless of the number of keratoplasty and young ages of patients. Transparent condition of transplant was for the period from 4 months to 2 years and there were only uveitis after keratoplasty, there were not any cases of endophthalmitis. Keywords: purulent corneal ulcer; HIV-infection; keratoplasty