Surgical Wound Infection in Renal Transplantation

Abstract

Despite immunosuppression, the incidence of surgical wound infection was minimal, comparing favorably to rates reported for renal transplantation with the use of systemic antibiotics. Possible explanations for the low incidence of surgical wound infections include local wound irrigation, meticulous hemostasis, improved organ procurement techniques, and continuity in perioperative care.

Infectious complications and antibiotic use in renal transplant recipients during a 1-year follow-up

“…The incidence of wound infection was low in the present study, as in other recent studies [19,20]. However, even without systemic perioperative prophylaxis, but only local antibiotic irrigation, the reported incidence of wound infection was only 2% in one study [21], suggesting that the lower incidences of wound infection in recent years may be partly due to improvements in surgical transplant techniques [21].…”

Perioperative Management of Medications for Psoriasis and Psoriatic Arthritis: A Review for the Dermasurgeon

“…The standard incidence rate of surgical wound infections in the immunosuppressed is believed to be 7%. Some studies noted increased infections with CsA while others did not 48–50 . Meticulous attention to surgical technique, wound irrigation, and management of wound hemostasis can reduce wound infections in the presence of immunosuppression 48 .…”

“…Some studies noted increased infections with CsA while others did not 48–50 . Meticulous attention to surgical technique, wound irrigation, and management of wound hemostasis can reduce wound infections in the presence of immunosuppression 48 . Given that transplantation protocols begin infusing CsA within 24 hours of surgery, the rare incidence of psoriasis rebound, and median time to psoriasis relapse of 56 to 196 days (relapse is defined as 50% return to baseline psoriasis after discontinuing drug), it appears that CsA may be safely held in the perioperative period if there are any concerns 51,52 .…”