Surgically treated spinal metastases: Do prognostic scores have a role?

Afsar, Afifa; Qadeer, Mohsin; Sharif, Salman

doi:10.4103/sni.sni_72_17

Cited by 7 publications

(1 citation statement)

References 12 publications

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“…The mechanical stability of the spine and the consideration of systemic diseases further help determine the necessity and feasibility of surgical intervention (13,14). Moreover, other scores for evaluating the prognostic efficacy of metastatic spine disease include the modified tokuhashi scores, the SINS scores and the tomita scores (16). Overall, these four methods play important roles in the treatment decision making of MST.…”

Section: Clinical Symptoms and The Therapeutic Principle For Mstmentioning

confidence: 99%

Clinical Therapy of Metastatic Spinal Tumors

Wei

et al. 2021

Front. Surg.

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Metastatic spinal tumors (MST) have high rates of morbidity and mortality. MST can destroy the vertebral body or compress the nerve roots, resulting in an increased risk of pathological fractures and intractable pain. Here, we elaborately reviewed the currently available therapeutic options for MST according to the following four aspects: surgical management, minimally invasive therapy (MIT), radiation therapy, and systemic therapy. In particular, these aspects were classified and introduced to show their developmental process, clinical effects, advantages, and current limitations. Furthermore, with the improvement of treatment concepts and techniques, we discovered the prevalent trend toward the use of radiation therapy and MIT in clinic therapies. Finally, the future directions of these treatment options were discussed. We hoped that along with future advances and study will lead to the improvement of living standard and present status of treatment in patients with MST.

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Section: Clinical Symptoms and The Therapeutic Principle For Mstmentioning

confidence: 99%

Clinical Therapy of Metastatic Spinal Tumors

Wei

et al. 2021

Front. Surg.

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Letter to the Editor Regarding: “The Use of Carbon Fiber-Reinforced Instrumentation in Patients with Spinal Oncologic Tumors: A Systematic Review of Literature and Future Directions”

Avallone,

Bonosi,

Tumbiolo

et al. 2023

World Neurosurgery

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Predictive Scores Underestimate Survival of Patients With Metastatic Spine Disease

Carrwik

Olerud

Robinson

2020

Spine

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Study Design. Retrospective cohort study. Objective. To validate the precision of four predictive scoring systems for spinal metastatic disease and evaluate whether they underestimate or overestimate survival. Summary of Background Data. Metastatic spine disease is a common complication to malignancies. Several scoring systems are available to predict survival and to help the clinician to select surgical or nonsurgical treatment. Methods. Three hundred fifteen adult patients (213 men, 102 women, mean age 67 yr) undergoing spinal surgery at Uppsala University Hospital, Sweden, due to metastatic spine disease 2006 to 2012 were included. Data were collected prospectively for the Swedish Spine Register and retrospectively from the medical records. Tokuhashi scores, Revised Tokuhashi Scores, Tomita scores, and Modified Bauer Scores were calculated and compared with actual survival data from the Swedish Population Register. Results. The mean estimated survival time after surgery for all patients included was 12.4 months (confidence interval 10.6–14.2) and median 5.9 months (confidence interval 4.5–7.3). All four scores had significant correlation to survival (P < 0.0001) but tended to underestimate rather than overestimate survival. Modified Bauer Score was the best of the four scores to predict short survival, both regarding median and mean survival. Tokuhashi score was found to be the best of the scores to predict long survival, even though the predictions were inaccurate in 42% of the cases. Conclusion. Predictive scores underestimate survival for the patients which might affect important clinical decisions. Level of Evidence: 3

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Surgically treated spinal metastases: Do prognostic scores have a role?

Cited by 7 publications

References 12 publications

Clinical Therapy of Metastatic Spinal Tumors

Clinical Therapy of Metastatic Spinal Tumors

Letter to the Editor Regarding: “The Use of Carbon Fiber-Reinforced Instrumentation in Patients with Spinal Oncologic Tumors: A Systematic Review of Literature and Future Directions”

Predictive Scores Underestimate Survival of Patients With Metastatic Spine Disease

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