Surrogates for validation of electron beam irradiation of foods

Rodríguez, Orlando; Me, Castell-Perez; N, Ekpanyaskun; Rg, Moreira; Castillo, Alejandro

doi:10.1016/j.ijfoodmicro.2006.01.041

Cited by 38 publications

(29 citation statements)

References 5 publications

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“…Twenty-five ml of non-irradiated bacteria were inactivated for 30 min in a water bath at 85°C, and were used as the heat-inactivated negative control. After irradiation, quantitative culture was performed to determine the concentration of replicating R. equi in each irradiated sample, and to calculate the D 10 -value, the dose required for 90% reduction of the initial population [40]. Experiments were conducted in triplicates, performed on 3 different days.…”

Section: Methodsmentioning

confidence: 99%

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Immunogenicity of an Electron Beam Inactivated Rhodococcus equi Vaccine in Neonatal Foals

et al. 2014

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Rhodococcus equi is an important pathogen of foals that causes severe pneumonia. To date, there is no licensed vaccine effective against R. equi pneumonia of foals. The objectives of our study were to develop an electron beam (eBeam) inactivated vaccine against R. equi and evaluate its immunogenicity. A dose of eBeam irradiation that inactivated replication of R. equi while maintaining outer cell wall integrity was identified. Enteral administration of eBeam inactivated R. equi increased interferon-γ production by peripheral blood mononuclear cells in response to stimulation with virulent R. equi and generated naso-pharyngeal R. equi-specific IgA in newborn foals. Our results indicate that eBeam irradiated R. equi administered enterally produce cell-mediated and upper respiratory mucosal immune responses, in the face of passively transferred maternal antibodies, similar to those produced in response to enteral administration of live organisms (a strategy which previously has been documented to protect foals against intrabronchial infection with virulent R. equi). No evidence of adverse effects was noted among vaccinated foals.

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Section: Methodsmentioning

confidence: 99%

“…The D 10 -value was calculated from the negative inverse of the slope from the linear mixed-effects regression of the irradiation dose on the logarithm 10 of the microbial population. [40]. Transmission electron microscopy data were descriptive only.…”

Section: Methodsmentioning

confidence: 99%

Immunogenicity of an Electron Beam Inactivated Rhodococcus equi Vaccine in Neonatal Foals

et al. 2014

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“…Electron-beam irradiation is used to inactivate food borne microorganisms during storage, and to guarantee the hygienic quality of foods (Sarrias et al, 2003). Electron-beam irradiation has been shown to destroy 99.9% of the major food pathogenic bacteria (Rodriguez et al, 2006), and it requires relatively short processing time and low equipment cost. Thus, it can be applicable as a preservation method for powdered weaning food to achieve microbial decontamination.…”

Section: Introductionmentioning

confidence: 99%

Inactivation of Enterobacter sakazakii, Bacillus cereus, and Salmonella typhimurium in powdered weaning food by electron-beam irradiation

Hong

Park

et al. 2008

Radiation Physics and Chemistry

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“…Hepatitis A virus inoculated on strawberries was fairly resistant to irradiation, with a D 10 value of 2.97 kGy (Bidawid et al, 2000). The pathogenic bacteria were more resistant to irradiation in the real fruit products compared to model foods or buffers (Niemira and Lonczynski, 2006;Rodriguez et al, 2006).…”

Section: New Efficacy Data Available In Scientific Literaturementioning

confidence: 98%

Scientific Opinion on the efficacy and microbiological safety of irradiation of food

2011

EFSA Journal

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The Opinion considers and discusses efficacy of food irradiation as the ability of irradiation to reduce food-borne pathogens in foods and microbiological safety of food irradiation as the contribution of irradiation to reduce the risks to human health from food-borne pathogens. The chemical safety and nutritional aspects of irradiation are addressed in a separate Opinion by the EFSA Panel on Food contact materials, enzymes, flavourings and processing aids. Potential microbiological risks linked to food irradiation are reviewed and the Opinion confirms that there are no microbiological risks for the consumer linked to the use of food irradiation and its consequences on the food microflora. The Opinion recommends that food irradiation should be based on risk assessment and on the desired risk reduction rather than on predefined food classes/commodities and doses as proposed in the past. In addition, with respect to efficacy and microbiological safety, it is recommended that upper dose limits for pathogen reduction should not be specified, since other constraints, such as undesirable chemical changes, will limit the doses applied. Irradiation should be considered as one of several approaches to reducing pathogens in food and thus helping to ensure protection of consumers' health. It is also recommended that food irradiation should only be used in conjunction with an integrated food safety management program and the Opinion concludes that when this includes GAP, GHP, GMP and HACCP, and depending on the dose applied, food irradiation can contribute to improved consumer safety by reducing food-borne pathogens. for the preparatory work on this scientific opinion.Efficacy and microbiological safety of irradiation of food 2 EFSA Journal 2011;9(4):2103 SUMMARY Following a request from the European Commission, the Panel on Biological Hazards (BIOHAZ Panel) was asked to deliver a scientific Opinion on the irradiation of food (efficacy and microbiological safety). Using the previous Opinions of the Scientific Committee on Food (SCF) on irradiation of food, EFSA was asked to establish whether the food classes/commodities and doses specified in those Opinions are still up-to-date to ensure consumer safety.Within this Opinion the BIOHAZ Panel considers and discusses efficacy of food irradiation as the ability of irradiation to reduce food-borne pathogens in foods and microbiological safety of food irradiation as the contribution of irradiation to reduce the risks to human health from food-borne pathogens. The chemical safety and nutritional aspects of irradiation are not considered in this Opinion as they are addressed in a separate Opinion by the EFSA Panel on Food contact materials, enzymes, flavourings and processing aids (CEF Panel).This Opinion also evaluates, for each food class/commodity requested, any recent change in biological hazards and food processing, preparation or consumption patterns which could have modified the risks for consumers and whether irradiation can be used in combination with other treatments and ho...

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Surrogates for validation of electron beam irradiation of foods

Cited by 38 publications

References 5 publications

Immunogenicity of an Electron Beam Inactivated Rhodococcus equi Vaccine in Neonatal Foals

Immunogenicity of an Electron Beam Inactivated Rhodococcus equi Vaccine in Neonatal Foals

Inactivation of Enterobacter sakazakii, Bacillus cereus, and Salmonella typhimurium in powdered weaning food by electron-beam irradiation

Scientific Opinion on the efficacy and microbiological safety of irradiation of food

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