Surrounding rim formation and reduction in size after radiofrequency ablation for primary breast cancer

Abstract

Our current series demonstrated the morphological characteristics on breast imaging after RFA plus radiation therapy. The size of the ablated area decreased over time. These findings are valuable for clinical follow-up of breast cancer patients undergoing RFA.

Minimally-invasive treatment of early stage breast cancer: A feasibility study using radiofrequency ablation under local anesthesia

“…In all cases the contrast enhancement in the target area had disappeared indicating complete treatment response. An ablation cavity could be seen surrounded by a peripheral ring as reported by other authors [10]. In two patients the MRI procedure before PRFA treatment lead to additional diagnostic investigations.…”

“…For radiological assessment MRI was the most significant improvement introduced in RF treatment of the breast since its inception. MRI has been proposed as a tool both for patient selection, especially to exclude patients with extensive intraductal carcinoma (EIC) [9], as well as a modality to evaluate therapeutic effect [10,20] where it was reported to reliably predict histologic findings [24]. None of the patients in our study showed EIC.…”

Pilot study of radiofrequency ablation therapy without surgical excision for T1 breast cancer: evaluation with MRI and vacuum-assisted core needle biopsy and safety management

“…Therefore, MRI can be used to predict complete tumor ablation after RFA [14]. In addition, MRI is valuable for clinical follow-up of breast cancer patients undergoing RFA [15]. Ablated tumor tissues were obtained using a Handy Mammotome (Tyco Health Care, King of Prussia, PA, USA) with an 8G needle under ultrasonography guidance.…”

Minimally invasive ablative techniques in the treatment of breast cancer: a systematic review and meta-analysis

“…A combination of follow-up and immediate or delayed surgical excision was performed in two studies (49 patients). [32, 33] Follow-up with imaging alone or imaging and core biopsies was performed in nine studies (220 patients) [21,23,24,30,31,60,66,68,73]. Reasons for performing a treat and resect study or a follow-up study were often not reported.…”

“…When looking at complete ablation rates of RFA studies that followed patients up with core needle biopsy (CNB) and imaging but without surgical excision, complete ablation was achieved in 98.0±4.0% (100/102) [30,32,66,68], in follow-up studies using cryo-ablation 100% (6/6) of patients had complete ablation [21] Treat and resect studies also undertook patient follow-up. RFA studies used MRI (n=6), US (n=4), mammography (n=2) or CT (n=1) for follow-up up to one month after surgical excision, laser ablation studies used MRI (n=2), US (n=1), CT (n=1) and mammography (n=1) for follow-up up to two weeks after surgical excision and every three months thereafter, cryo-ablation studies used MRI (n=3) or US (n=1) for follow-up up to one month after surgical excision, HIFU studies used MRI (n=5) for follow-up up to three weeks J U S T A C C E P T E D after surgical excision, and microwave ablation studies used MRI (n=1) or US (n=1) up to three weeks prior to surgical excision.…”