Surto de parvovirose cardíaca em filhotes de cães no Brasil

Abstract

RESUMO.-Descrevem-se os aspectos epidemiológicos, clí-nicos, patológicos e imuno-histoquímicos de um surto de parvovirose cardíaca em filhotes de cães. O surto ocorreu em um canil localizado na cidade de Parnamirim, Rio Grande do Norte, região Nordeste do Brasil. De uma ninhada de nove filhotes, um foi natimorto e seis morreram entre 35-57 dias de idade após apresentarem sinais clínicos cardiorrespiratórios com evolução de 10 minutos a três dias. Dos seis filhotes que morreram, dois foram encaminhados para necropsia. No exame macroscópico, ambos os animais apresentaram discreta efusão pericárdica, coração marcadamente globoso, difusa palidez nas superfícies epicárdica e miocárdica e dilatação da cavidade ventricular esquerda. Nos pulmões, observaram-se áreas multifocais avermelhadas na superfície pleural e ao corte fluía líquido espumoso e levemente avermelhado. O fígado estava difusamente aumentado de tamanho, com acentuação do padrão lobular e com áreas pálidas entremeadas por áreas escuras que, ao corte, se aprofundavam ao parênquima. Microscopicamente observou-se miocardite linfohistiocítica, necrosante, associada a fibrose intersticial e corpúsculos de inclu- We describe the epidemiological, clinical, pathological and immunohistochemical aspects of parvoviral myocarditis outbreak in puppies. The outbreak occurred in a kennel located in Parnamirim, Rio Grande do Norte, Northeastern of Brazil. In a litter of nine pups, one was stillbirth and six died between 35-57 days of age after cardiopulmonary clinical signs with evolution of 10 minutes to three days. Of the six puppies that died, two were sent for necropsy. On gross examination, both animals had discreet pericardial effusion, markedly distended heart, diffuse pallor in epicardial and myocardial surfaces and dilation of the left ventricular cavity. The lungs were observed multifocal reddish areas in the pleural surface and at cutting flowed foamed and slightly red liquid. The liver was diffusely increased in size, with lobular standard accentuation and pale areas interspersed with dark areas wich deepened in the parenchyma. Microscopically observed linfohistiocítica myocarditis, necrotizing, associated with interstitial fibrosis and basophilic intranuclear viral inclusions corpuscles in cardiomyocytes. In the lungs there were edema and interstitial pneumonia and in the liver was noted centrilobular to mediozonal degeneration and necrosis associated with congestion and hemorrhage. The diagnosis was confirmed by immunohistochemistry. The parvoviral myocarditis can occasionally occur in puppies of bitches that have not been effectively vaccinated. This clinical form of the disease characterized by cardiorespiratory changes and hyperacute or acute death of the affected animals.INDEX TERMS: Parvoviral myocarditis, newborn dog disease, viral myocarditis, Parvovirus.

Genetic characterization and predominance of the new CPV-2a variant in clinical cases of canine parvovirus in the western region of Rio Grande do Sul, Brazil

“…High mortality is characteristic of canine parvovirosis, and several studies indicate varying degrees of lethality (CALDERON et al, 2011;DECARO & BUONAVOGLIA, 2012;NANDI et al, 2010;SOUTO et al, 2018). Young animals under the age of 6 months are the most affected, probably due to the association of factors such as reduced maternal immunity, high intestinal mitosis rate, and presence of co-infections that can aggravate the infection (DECARO et al, 2005;DECARO et al, 2020;SOUTO et al, 2018). Dogs older than two years have already developed natural immunity from exposure to the agent or have higher vaccination coverage (DECARO et al, 2020).…”

“…was diagnosed (ID # 12). In newborn dogs, myocarditis is another lesion that can occur; however, it is underreported, and this may be associated with the lack of clinical and histopathological diagnosis (SOUTO et al, 2018).…”

Hipoplasia Cerebelar Em Neonatos Felinos, Secundária À Transmissão Vertical Da Panleucopenia Felina

“…Assim, as parvoviroses são as causas mais comuns de desenvolvimento de hipoplasia cerebelar em felinos (COSTA, 2015), mas também estão relacionadas com tal alteração em frangos de corte (MARUSAK et al, 2010), bovinos (HUBNER et al, 1996) e suínos (RUIZ, 2017). Entretanto, tal observação não foi observada em potros (MOREIRA, 2014) e, no caso de neonatos caninos, o maior órgão alvo de infecção pelo parvovírus, em transmissão transplacentária, é o miocárdio (SOUTO et al, 2018).…”

Atualidades Na Saúde E Bem-Estar Animal, Volume 7

“…A Parvovirose canina é uma doença infectocontagiosa de distribuição mundial causadora de gastroenterite hemorrágica grave em cães (PAES, 2016;SOUTO et al, 2018).…”