Surveillance épidémiologique de la rage humaine dans un contexte d’endémie de rage canine en Cote d’Ivoire

Tiembré, I.; Dagnan, S.; Douba, Alfred; Adjogoua, Edgard Valéry; Bourhy, Hervé; Dacheux, Laurent; Kouassi, Léonard; Dosso, M.; Odehouri-Koudou, P.

doi:10.1016/j.medmal.2010.01.008

Cited by 13 publications

(19 citation statements)

References 6 publications

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“…In addition, these cases are evidence of a much larger pool of animal exposure cases that do not seek appropriate PEP within the healthcare system and therefore are currently not captured by surveillance. A previous study in Côte d’Ivoire recorded 26 national cases of human rabies in the 8½ years between January 2001 and June 2009 [ 6 ], which is lower than the 50 cases reported here for the entire population for the three years between 2014 to 2016. This suggests that the reporting within the reinforced NIPH surveillance system has improved over the system in previous years.…”

Section: Discussioncontrasting

confidence: 74%

“…During the three years of this study, the surveillance system recorded 50 cases of human rabies (15 to 18 cases annually) in Côte d’Ivoire. As found in other studies in Côte d’Ivoire, many of the cases were in children <15 years old and dog bites were the most common route of viral transmission [ 6 , 11 , 12 ]. None of these cases presented at a NIPH local unit prior to manifesting the clinical signs and none had received PEP.…”

Section: Discussionsupporting

confidence: 53%

“…Therefore, the real numbers of animal exposures and rabies cases in Côte d’Ivoire are unknown and are probably much higher than reported by the NIPH in previous years. For example, the NIPH network detected 26 cases of human rabies between 2001 and 2009, only 4 of which were laboratory confirmed [ 6 ]. In contrast, Hampson et al estimated 569 (95% confidence interval, 298–1352) cases of human rabies per year.…”

Section: Introductionmentioning

confidence: 99%

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Human rabies in Côte d'Ivoire 2014-2016: Results following reinforcements to rabies surveillance

et al. 2018

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In Côte d’Ivoire, rabies is endemic and remains largely uncontrolled. The numbers of human exposures and rabies cases are unknown and are probably much higher than reported. Data on human rabies cases are collected by the National Institute of Public Health (NIPH) Anti-rabies Center in Abidjan through a network of 28 NIPH local units, which cover the population of the entire country. During 2014, the NIPH initiated a program to reinforce the human rabies surveillance system in those 28 NIPH local units, with specific goals of improving the infrastructure, training, communication, and government involvement. Here, we report the progress and findings during 2014–2016. The reinforced system recorded 50 cases of human rabies (15–18 cases/year; annual incidence = 0.06−0.08 per 100,000) and more than 30,000 animal exposures (annual incidence = 41.8−48.0 per 100,000). Almost one-half of the human rabies cases were in children ≤15 years old. All were fatal and dog bites were the most common route by which rabies virus was transmitted. In the 32 cases where samples of sufficient quality for analysis were available, rabies was confirmed by reverse transcription-polymerase chain reaction RT-PCR. Post-exposure prophylaxis with rabies vaccine was administered to all animal exposure victims presenting at the NIPH local units, although only about 57% completed the full immunization schedule. All available reports were provided by the NIPH local units, indicating effective communication between them and the NIPH Anti-rabies Center. These findings indicate that the reinforcements resulted in highly specific detection of human rabies, provided detailed epidemiological data about these cases, and improved estimates of animal exposure numbers. These represent substantial advances, but further improvements to the surveillance system are needed to increase disease awareness and capture cases that are currently missed by the system. In the future, better communication between local health centers and the NIPH units, surveillance at the local health center level, and increased veterinarian engagement will help provide a more complete picture of the rabies burden in Côte d’Ivoire.

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Section: Discussioncontrasting

confidence: 74%

Section: Discussionsupporting

confidence: 53%

Section: Introductionmentioning

confidence: 99%

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Human rabies in Côte d'Ivoire 2014-2016: Results following reinforcements to rabies surveillance

et al. 2018

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“…The disease could be controlled by vaccination, but still a neglicted disease in most infected countries. Rabies is enzootic in Ivory Coast [1]. To regulate the international movement of domestic carnivores from infected countries to free territories from rabies, a system combining the anti-rabies vaccination of the animal and serological testing was launched.…”

Section: Introductionmentioning

confidence: 99%

Assessment of anti Rabies post-vaccinal immunity in domestic carnivores pets in low resources setting

Koffl¹,

Kouakou

et al. 2020

Preprint

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Objective Rabies is a zoonotic disease transmissible to humans mainly by dogs. It is a vaccine preventable disease. In Ivory Coast, canine rabies is a prioritary and notifiable animal disease since 1962. Evaluation of post-vaccination immunity against rabies was undertaken between 2003 and 2009 by an immunoenzymatic test Platelia Rabies II ELISA Kits (Bio-Rad). We aim to investigate anti Rabies vaccination efficacy in Ivory Coast, using data obtained purposely for antibody quantification prior to international movement of pets. Results A total of 527 dogs and cats sera were analyzed. Generally cats had developed higher level of post vaccinal immunity than dogs. We have found that more than 95.80% (114/119) of cats had a serum with antibodies titer above 0.5 EU /ml so like 74.75% (n = 305) of dogs. Undetectable or insufficient level of seroconversion was noted either in the canine specie (25.25%) or in cats (4.2%). Multivaccined Dogs, older than 4 years, represented the most important group (62.25%) of seronegative dog population. Associated with vaccination, serological results were used as data based-evidence in compliance with official requirements governing free movements of pets from rabies-infected to rabies-free european countries. Keywords : Ivory Coast, Rabies, ELISA, post-vaccinal immunity, dogs, cats

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“…In Ivory Coast, 31,492 animal exposures and 50 suspected human cases were reported, and 32 of the 39 samples submitted for testing were laboratory confirmed [ 32 ]. By comparison, 26 cases of human rabies for the entire country were reported to the Ivory Coast national health ministry between 2001 and 2009, only four of which were sampled and then confirmed by postmortem laboratory analysis [ 35 ].…”

mentioning

confidence: 99%

Bolstering human rabies surveillance in Africa is crucial to eliminating canine-mediated rabies

et al. 2018

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Surveillance épidémiologique de la rage humaine dans un contexte d’endémie de rage canine en Cote d’Ivoire

Cited by 13 publications

References 6 publications

Human rabies in Côte d'Ivoire 2014-2016: Results following reinforcements to rabies surveillance

Human rabies in Côte d'Ivoire 2014-2016: Results following reinforcements to rabies surveillance

Assessment of anti Rabies post-vaccinal immunity in domestic carnivores pets in low resources setting

Bolstering human rabies surveillance in Africa is crucial to eliminating canine-mediated rabies

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