Surveillance of patients with inflammatory bowel disease

Yu, Jessica X.; East, James E.; Kaltenbach, Tonya

doi:10.1016/j.bpg.2016.10.014

Cited by 15 publications

(13 citation statements)

References 47 publications

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“…Because IBD-related colorectal cancer in most instances develops from dysplasia, it serves as the best marker of cancer risk in patients with IBD. 34,35 Although it is readily detectable for an advanced tumor endoscopically ( Figure 5), the precancerous and early cancer lesions are often flat and difficult to be distinguished from an inflamed and distorted background. Diagnosis of colitis-associated dysplasia and early cancer is one of the big challenges in gastrointestinal endoscopy.…”

Section: Surveillance and Prevention Of Colitis-related Colorectal Camentioning

confidence: 99%

“…Diagnosis of colitis-associated dysplasia and early cancer is one of the big challenges in gastrointestinal endoscopy. 34,35 Multiple societies including the American Gastroenterology Association, 36 the American College of Gastroenterology, 37 the American Society for Gastrointestinal Endoscopy, 38 the SCENIC (Surveillance for Colorectal Endoscopic Neoplasia Detection and Management in Inflammatory Bowel Disease Patients: International Consensus Recommendations) group, 39 European group, 40 and the British Gastroenterology Society 41 have published recommended surveillance guidelines, although they are all quite similar. These recommendations are on the basis of disease duration and extent of disease.…”

Section: Surveillance and Prevention Of Colitis-related Colorectal Camentioning

confidence: 99%

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Intestinal and Extraintestinal Cancers Associated With Inflammatory Bowel Disease

Chang

et al. 2018

Clinical Colorectal Cancer

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Inflammatory bowel disease (IBD) with its 2 most common entities, ulcerative colitis and Crohn's disease, causes an increased risk of developing intestinal cancers. In fact, malignancies are the second most common cause of death after cardiovascular diseases in both sexes of patients with IBD. Risk factors for colorectal cancer in IBD correlate with the duration of the disease, extent of disease, the association with primary sclerosing cholangitis, family history, and early age at onset. Patients with IBD also have an increased risk for developing a variety of extraintestinal malignancies. In particular, lymphomas, mostly non-Hodgkin lymphomas and skin cancers, are more frequently observed in IBD patients. Longstanding inflammation and the degree of immunosuppression as a result of IBD treatment appear to be the main driving factors for IBD-related carcinogenesis. This review provides an update on the clinical and pathological features of IBD-related intestinal and extraintestinal malignancies.

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Section: Surveillance and Prevention Of Colitis-related Colorectal Camentioning

confidence: 99%

Section: Surveillance and Prevention Of Colitis-related Colorectal Camentioning

confidence: 99%

Intestinal and Extraintestinal Cancers Associated With Inflammatory Bowel Disease

Chang

et al. 2018

Clinical Colorectal Cancer

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“…Although uncommon, neoplastic changes can develop in adolescents or young adults. While debatable, long-term duration, extensive colitis, chronic active inflammation, and presence of primary sclerosing cholangitis may be influential factors for the development of colorectal malignancies [2235]. Guidelines in the United States, Britain, and European Crohn's and Colitis Organisation (ECCO) recommend surveillance colonoscopy every 1-2 years after 8-10 years duration of disease.…”

Section: Neoplastic Changesmentioning

confidence: 99%

“…Guidelines in the United States, Britain, and European Crohn's and Colitis Organisation (ECCO) recommend surveillance colonoscopy every 1-2 years after 8-10 years duration of disease. For high-risk patients, earlier and more frequent surveillance should be considered [223536]. Identification of carcinoma or non-adenoma-like dysplasia associated lesion or mass, high-grade dysplasia, or multifocal low grade dysplasia from the colon or rectum should prompt consideration of total proctocolectomy.…”

Section: Neoplastic Changesmentioning

confidence: 99%

Surgery in Pediatric Crohn's Disease: Indications, Timing and Post-Operative Management

Kim

2017

Pediatr Gastroenterol Hepatol Nutr

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Pediatric onset Crohn's disease (CD) tends to have complicated behavior (stricture or penetration) than elderly onset CD at diagnosis. Considering the longer duration of the disease in pediatric patients, the accumulative chance of surgical treatment is higher than in adult onset CD patients. Possible operative indications include perianal CD, intestinal stricture or obstruction, abdominal abscess or fistula, intestinal hemorrhage, neoplastic changes and medically untreatable inflammation. Growth retardation is an operative indication only for pediatric patients. Surgery can affect a patient's clinical course, especially for pediatric CD patient who are growing physically and mentally, so the decision should be made by careful consideration of several factors. The complex and diverse clinical conditions hinder development of a systemized treatment algorithm. Therefore, timing of surgery in pediatric CD patients should be determined with individualized approach by an experienced and well organized multidisciplinary inflammatory bowel disease team. Best long-term outcomes will require proactive post-operative monitoring and therapeutic modifications according to the conditions.

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“…[1][2][3][4] However, anxiety, pain, fear and adverse gastrointestinal reactions may cause subjects to be less cooperative during endoscopic procedures, and may even cause harmful cardiovascular adverse events. [5][6][7] Thus, the role of sedation in endoscopy is therefore very important, with various sedative agents commonly used during endoscopic procedures.…”

Section: Introductionmentioning

confidence: 99%

Effect of dexmedetomidine in the prophylactic endoscopic injection sclerotherapy for oesophageal varices: a study protocol for prospective interventional study

Nishikawa

Iwata

Ishii

et al. 2017

BMJ Open Gastroenterol

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BackgroundDexmedetomidine (DEX) is a novel, highly selective α2-adrenoceptor agonist that elicits sedative, amnestic, sympatholytic and analgesic effects in patients. Several Japanese investigators have reported the clinical usefulness of DEX for sedation in endoscopic therapies for gastrointestinal malignancies; however, there have been limited data regarding the usefulness and safety of DEX for sedation during endoscopic procedures for oesophageal varices (OVs), such as endoscopic injection sclerotherapy (EIS). In this prospective, single-arm interventional study, we aimed to elucidate these issues.MethodsPatients who require two or more sessions of prophylactic EIS for the treatment of OVs will be enrolled in this prospective interventional study. EIS procedures include two methods: (1) sedation during endoscopic procedures will be performed using conventional methods (pentazocine (PNZ) and midazolam (MDZ)), and (2) sedation during endoscopic procedures will be performed using PNZ, low-dose MDZ and DEX. These two methods were randomly assigned in the first and second EIS. The effect and safety of these two procedures with respect to patient sedation are to be compared with the degree of sedation evaluated using the Bispectral Index monitoring system (Aspect Medical Systems, Norwood, Massachusetts, USA).Ethics and disseminationThis study received approval from the Institutional Review Board at Hyogo College of Medicine (approval no. 2324). The authors are committed to publishing the study results as widely as possible in peer-reviewed journals, and to ensuring that appropriate recognition is provided to everyone who is working on this study.Trial registration numberUMIN000026688; Pre-results.

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Surveillance of patients with inflammatory bowel disease

Cited by 15 publications

References 47 publications

Intestinal and Extraintestinal Cancers Associated With Inflammatory Bowel Disease

Intestinal and Extraintestinal Cancers Associated With Inflammatory Bowel Disease

Surgery in Pediatric Crohn's Disease: Indications, Timing and Post-Operative Management

Effect of dexmedetomidine in the prophylactic endoscopic injection sclerotherapy for oesophageal varices: a study protocol for prospective interventional study

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