Surveillance report of Zika virus among Canadian travellers returning from the Americas

Boggild, Andrea K.; Geduld, J; Libman, Michael; Yansouni, Cédric P.; McCarthy, Anne; Hájek, Jan; Ghesquière, Wayne; Mirzanejad, Yazdan; Vincelette, Jean; Kuhn, Susan; Plourde, Pierre; Chakrabarti, Sumontra; Freedman, David O.; Kain, Kevin C.

doi:10.1503/cmaj.161241

Cited by 30 publications

(19 citation statements)

References 25 publications

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“…2 We recognize that understanding the intricacies of the CanTravNet data would be difficult without first-hand experience of our network and its patient population. CanTravNet is a consortium of posttravel (not pretravel) tropical medicine clinics situated across Canada, and patients enter our system after referral, mostly via emergency departments or primary care.…”

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confidence: 99%

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Boggild

Libman

Yansouni

et al. 2017

CMAJ

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Section: Response To "Selection Bias"mentioning

confidence: 99%

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Libman

Yansouni

et al. 2017

CMAJ

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“…Knowledge on perinatal infection with Zika and the neurodevelopmental sequelae of affected infants is rapidly evolving. 36 A Canadian study found that 5% of travelers developed neurologic complications such as Guillain-Barre syndrome with Zika, suggesting there is much to learn with this disease in nonperinatally acquired infections. 37 At this time, treatment is primarily supportive.…”

Section: Other Causes Of Fevermentioning

confidence: 99%

Fever in the Returning Traveler

Huang

Schlaudecker

2018

Infectious Disease Clinics of North America

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Millions of children travel annually, whether they are refugees, international adoptees, visitors, or vacationers. Although most young travelers do well, many develop a febrile illness during or shortly after their trips. Approaching a fever in the returning traveler requires an appropriate index of suspicion to diagnose and treat in a timely manner. As many as 34% of patients with recent travel history are diagnosed with routine infections, but serious infections such as malaria, enteric fever, and dengue fever should be on the differential diagnosis due the high morbidity and mortality in children.

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“…Efficient serological and molecular detection techniques are warranted for improved surveillance to prevent the spread of disease by adopting timely and appropriate control measures (Waggoner and Pinsky, 2016 ; Sharma and Lal, 2017 ). In North America, the GeoSentinel Surveillance Network data platform has been used to track Canadian travelers displaying signs of acute ZIKV infection and fetal neurologic anomalies between October 2015 and September 2016 on the CanTravNet site (Boggild et al, 2017 ).…”

Section: Introductionmentioning

confidence: 99%

Advances in Diagnosis, Surveillance, and Monitoring of Zika Virus: An Update

et al. 2018

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Zika virus (ZIKV) is associated with numerous human health-related disorders, including fetal microcephaly, neurological signs, and autoimmune disorders such as Guillain-Barré syndrome (GBS). Perceiving the ZIKA associated losses, in 2016, the World Health Organization (WHO) declared it as a global public health emergency. In consequence, an upsurge in the research on ZIKV was seen around the globe, with significant attainments over developing several effective diagnostics, drugs, therapies, and vaccines countering this life-threatening virus at an early step. State-of-art tools developed led the researchers to explore virus at the molecular level, and in-depth epidemiological investigations to understand the reason for increased pathogenicity and different clinical manifestations. These days, ZIKV infection is diagnosed based on clinical manifestations, along with serological and molecular detection tools. As, isolation of ZIKV is a tedious task; molecular assays such as reverse transcription-polymerase chain reaction (RT-PCR), real-time qRT-PCR, loop-mediated isothermal amplification (LAMP), lateral flow assays (LFAs), biosensors, nucleic acid sequence-based amplification (NASBA) tests, strand invasion-based amplification tests and immune assays like enzyme-linked immunosorbent assay (ELISA) are in-use to ascertain the ZIKV infection or Zika fever. Herein, this review highlights the recent advances in the diagnosis, surveillance, and monitoring of ZIKV. These new insights gained from the recent advances can aid in the rapid and definitive detection of this virus and/or Zika fever. The summarized information will aid the strategies to design and adopt effective prevention and control strategies to counter this viral pathogen of great public health concern.

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Surveillance report of Zika virus among Canadian travellers returning from the Americas

Cited by 30 publications

References 25 publications

Response to “Selection bias”

Response to “Selection bias”

Fever in the Returning Traveler

Advances in Diagnosis, Surveillance, and Monitoring of Zika Virus: An Update

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