“…Of the 179 respondents participating in a recorded audience response session at the recent American Society of Dermatopathology annual meeting, 127 (71%) had encountered a melanoma ''on re-excision of a lesion diagnosed as dysplastic nevus with moderate atypia within the past 5 years,'' with 49% (81 of 164) having encountered this situation within the past year. 3 The reported 2.0 % rate of melanoma occurring at the site of histologically transected mild or moderately dysplastic nevi (most of which had grossly positive margins) but only a 0.6% rate of melanoma developing at the site of nevi that had been re-excised 4 may be contributing to the variability in the management of moderate dysplastic nevi by academic dermatologists that was noted by Tessiatore et al 1 There may be good reasons why academic dermatologists continue to perform rebiopsy of or excise some moderate dysplastic nevi. It is hoped that continued study of this common problem will lead to practical and widely accepted standards for both the reporting and management of moderately dysplastic nevi.…”