Survey of Adult Influenza Vaccination Practices and Perspectives Among US Primary Care Providers (2016–2017 Influenza Season)

Cataldi, Jessica R.; O’Leary, Sean T.; Lindley, Megan C.; Hurley, Laura P.; Allison, Mandy A.; Brtnikova, Michaela; Beaty, Brenda; Crane, Lori A.; Kempe, Allison

doi:10.1007/s11606-019-05164-7

Cited by 13 publications

(11 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Another point of interest was that the frequency of the sampled HCWs who recommended the vaccinations to the patients was very low, as less than one in five declared to make the recommendation. Previous studies conducted in the United States highlighted that 98% of primary care providers recommended influenza vaccine to those ≥ 65 years, 90% to adults 50-64 years, and 75% to 19-49 years [25]; 54.4% and 54.7% of physicians recommended diphtheria-tetanus-acellular-pertussis and zoster vaccines, respectively, to patients ≥ 65 years [26]; and 94.7% of clinicians recommended vaccines to adults [27]. In the present study, HCWs were most likely to feel confident in trusting online information sources to search about vaccinations.…”

Section: Discussionmentioning

confidence: 99%

Healthcare Workers’ Knowledge, Attitudes, and Practices about Vaccinations: A Cross-Sectional Study in Italy

et al. 2020

View full text Add to dashboard Cite

The cross-sectional study assessed the knowledge, attitudes, and practices regarding the recommended vaccinations and factors affecting such outcomes among a sample of healthcare workers (HCWs) in public hospitals in Italy. Only 14.1% knew all the recommended vaccinations for HCWs. Physicians and those who had received information about vaccinations from scientific journals, educational activities, or professional associations were more likely to have this knowledge, while those aged 36–45 were more likely to have less knowledge than those in the age group below 36 years. Only 57.3% agreed that the information received about vaccinations was reliable. Respondents who had children, who worked in pediatric/neonatal wards, who were more knowledgeable, or who did not need further information about vaccinations considered the available information to be reliable. Only 17.7% of respondents always recommended vaccinations to their patients. This behavior was more likely to occur in physicians, in HCWs, in pediatric/neonatal wards, in those who considered the information received about vaccinations reliable, and in those who considered themselves to be at high risk of transmitting an infectious disease to their patients. Health promotion programs and efforts are needed to improve the level of knowledge about vaccinations and immunization coverage among HCWs.

show abstract

Section: Discussionmentioning

confidence: 99%

Healthcare Workers’ Knowledge, Attitudes, and Practices about Vaccinations: A Cross-Sectional Study in Italy

et al. 2020

View full text Add to dashboard Cite

show abstract

“…Measures of prevention and treatment of rhinovirus and coronavirus infections do not exist, albeit several virus proteins e. g. viral capsid, protease, and polymerase proteins have been identified as valid targets of inhibitors [7][8][9]. Even though influenza vaccines do exist, they are suboptimal applied [10][11][12][13]. The arsenal of drugs for treatment of influenza is limited.…”

Section: Introductionmentioning

confidence: 99%

Comparative in vitro analysis of inhibition of rhinovirus and influenza virus replication by mucoactive secretolytic agents and plant extracts

Walther

Döring

Schmidtke

2020

BMC Complement Med Ther

View full text Add to dashboard Cite

Background Rhinoviruses and influenza viruses cause millions of acute respiratory infections annually. Symptoms of mild acute respiratory infections are commonly treated with over-the-counter products like ambroxol, bromhexine, and N-acetyl cysteine, as well as of thyme and pelargonium extracts today. Because the direct antiviral activity of these over-the-counter products has not been studied in a systematic way, the current study aimed to compare their inhibitory effect against rhinovirus and influenza virus replication in an in vitro setting. Methods The cytotoxicity of ambroxol, bromhexine, and N-acetyl cysteine, as well as of thyme and pelargonium extracts was analyzed in Madin Darby canine kidney (MDCK) and HeLa Ohio cells. The antiviral effect of these over-the-counter products was compared by analyzing the dose-dependent inhibition (i) of rhinovirus A2- and B14-induced cytopathic effect in HeLa Ohio cells and (ii) of influenza virus A/Hong Kong/68 (subtype H3N2)- and A/Jena/8178/09 (subtype H1N1, pandemic)-induced cytopathic effect in MDCK cells at non-cytotoxic concentrations. To get insights into the mechanism of action of pelargonium extract against influenza virus, we performed time-of-addition assays as well as hemagglutination and neuraminidase inhibition assays. Results N-acetyl cysteine, thyme and pelargonium extract showed no or only marginal cytotoxicity in MDCK and HeLa Ohio cells in the tested concentration range. The 50% cytotoxic concentration of ambroxol and bromhexine was 51.85 and 61.24 μM, respectively. No anti-rhinoviral activity was detected at non-cytotoxic concentrations in this in vitro study setting. Ambroxol, bromhexine, and N-acetyl cysteine inhibited the influenza virus-induced cytopathic effect in MDCK cells no or less than 50%. In contrast, a dose-dependent anti-influenza virus activity of thyme and pelargonium extracts was demonstrated. The time-of addition assays revealed an inhibition of early and late steps of influenza virus replication by pelargonium extract whereas zanamivir acted on late steps only. The proven block of viral neuraminidase activity might explain the inhibition of influenza virus replication when added after viral adsorption. Conclusion The study results indicate a distinct inhibition of influenza A virus replication by thyme and pelargonium extract which might contribute to the beneficial effects of these plant extracts on acute respiratory infections symptoms.

show abstract

“…Standing orders and electronic alerts were commonly used in the practice-based immunization. 19 In addition, Internal medicine specialists were reported to be higher rates of assessing, recommending, and stocking for most vaccine types, notably susceptible adults under risk with comorbidities. 20 Compatible with the literature, in the present study, influenza, and PCV13 were the most recommended vaccines, and primary physicians and internists suggest and review the vaccination history frequently.…”

Section: Discussionmentioning

confidence: 99%

The Awareness and Attitude of Physicians to Older Adult Routine Vaccination Scheme

Bulut¹,

Badak²,

Aksoy³

et al. 2022

CIA

View full text Add to dashboard Cite

Immunization is one of the main components of preventive medicine measures. Influenza, pneumococcal, tetanus, and shingles vaccines are recommended for older adults routinely. This study aimed to show the knowledge and attitudes of the physicians to older adults' vaccination schemes. Patients and Methods: An electronic self-reported questionnaire was sent to physicians between March and July 2021 in Turkey. Sociodemographic characteristics, professional experience, area of expertise, and practice setting of the participants were recorded. As multiple-choice questions; the routinely recommended vaccines, and vaccines suggested in their daily practice before and after the COVID-19 pandemic were enquired. Results: A total of 435 participants were included in the study. 43.9% of the patients were primary family physicians, and 36.8% were internists. 63.4% of the participants had reported reviewing the National Vaccination Scheme. 94.5% of the medical doctors indicated that they had recommended any vaccination to their patients. 20.9% of the practitioners could select four or five of the routinely recommended vaccines. Reviewing the National Adult Vaccination Scheme and being an internist were positively related to predicting the recommended vaccines. The recommendation rates of influenza and pneumococcal conjugate (PCV13) were seen at 88% and 78%, respectively. Except for PCV13, recommendation rates of other routine vaccines were decreased after the pandemic. Conclusion: Awareness of routine vaccination schedules should be improved among health-care professionals, and reminders for immunization should be provided periodically in each health-care setting.

show abstract

Survey of Adult Influenza Vaccination Practices and Perspectives Among US Primary Care Providers (2016–2017 Influenza Season)

Cited by 13 publications

References 24 publications

Healthcare Workers’ Knowledge, Attitudes, and Practices about Vaccinations: A Cross-Sectional Study in Italy

Healthcare Workers’ Knowledge, Attitudes, and Practices about Vaccinations: A Cross-Sectional Study in Italy

Comparative in vitro analysis of inhibition of rhinovirus and influenza virus replication by mucoactive secretolytic agents and plant extracts

The Awareness and Attitude of Physicians to Older Adult Routine Vaccination Scheme

Contact Info

Product

Resources

About