Survey of anaerobic susceptibility patterns: A French multicentre study

Antimicrobial Resistance and β-Lactamase Production of Clinical Isolates of <i>Prevotella </i>and <i>Porphyromonas</i> Species

“…None of our Porphyromonas species produced ␤ -lactamase. A similar result was also reported by Mory et al [28] and Kuriyama et al [23]. In contrast, Aldridge [6] reported a low ␤ -lactamase production, found at a rate of 4.5% in clinical Porphyromonas species, and Jacobs et al [29] reported a few ␤ -lactamase-positive P. gingivalis strains.…”

In Vitro Activities of a New Des-Fluoro(6) Quinolone, Garenoxacin, against Clinical Anaerobic Bacteria

“…Overall, the MICs of garenoxacin for 50 and 90% of the strains tested (in micrograms per milliliter) were as follows: Bacteroides fragilis group, 0.5 and 2; Prevotella spp., 0. 25 Resistance to ␤-lactams, clindamycin, and metronidazole among anaerobes is increasing worldwide (5,10,16,20,21,23). The older quinolones ciprofloxacin and levofloxacin provide only limited activity against many anaerobic species (7,8,11,14,28,31).…”

Cross-Infection Due to Imipenem-Resistant Bacteroides fragilis Associated with a Totally Implantable Venous Port

“…Antibiotyping by the disk diffusion method (23 tested antibiotics) showed that Bf1149 and Bf1150 were resistant to all ␤-lactams including imipenem, in contrast with the two other strains (MICs of 128 mg/liter and 0.5 mg/liter, respectively) ( Table 1). Imipenem resistance is an exceptional trait among B. fragilis strains (0 to 3%) (6,16,21). This resistance is due to the production of a group 3a class B metallo-␤-lactamase encoded by the silent cfiA chromosomal gene, the expression of which is promoted by the insertion of an insertion element (IS) immediately upstream (1,18,19,21).…”