Survey of aspiration biopsy cytology of the breast

Abstract

Based on the team approach, the Papanicolaou method, simple equipment, and special criteria of malignancy, aspiration biopsy cytology of the breast is reviewed.

The Gray Zone in Breast Fine Needle Aspiration Cytology

“…1,6 Fine needle aspiration of the breast has some unavoidable limitations. Excluding lack of knowledge and experience of the cytopathologist, they are inadequate sampling, poor preservation and poor cellular yield of tumors with fibrotic stroma or cystic component.…”

“…1 There is a group of pathologies between benign and malignant lesions that causes diagnostic difficulty, the "gray zone," in which unequivocal diagnoses of benign or malignant cannot be reached based on the FNAC findings. 2,3 Excluding technical factors and the knowledge and experience of the individual cytopathologist, there are difficulties due to overlap of the criteria used to distinguish benign from malignant.…”

Is a diagnosis of infiltrating versus in Situ ductal carcinoma of the breast possible in fine-needle aspiration specimens?

“…4 Despite prior studies reporting its inability to separate DCIS from IDC, [5][6][7][8] efforts to reevaluate this issue have been made sporadically. 9 -11 To determine whether the diagnosis of stromal invasion can be made based on FNA findings, we studied FNA specimens from 36 breast lesions that had been confirmed histologically as being exclusively DCIS, and we compared the features from these aspirates with those of IDC aspirates.…”

Guideline zur Abklärung des palpablen Mammabefundes

“…In der Ultraschalluntersuchung kann ihre Komprimierbarkeit nachgewiesen werden. Die Punktion sollte in 90 -95 % der Fälle reprä-sentativ sein [33] 4 . Mit der zytologischen Untersuchung eines Feinnadelpunktates kann meistens die morphologische Diagnose sowohl in bezug auf Dignität wie auch Art der Veränderung gestellt werden.…”