Survey of Complications of Indocyanine Green Angiography in Japan

Obana, Akira; Miki, Tokuhiko; Hayashi, Kazuhiko; Takeda, Masako; Kawamura, Akira; Mutoh, Tatsushi; Harino, Seiyo; Fukushima, Ichiro; Komatsu, Hironori; Takaku, Yasuharu; Shiraga, Fumio; Matsuhashi, Hideaki; Torii, Yoshihiko; Masaoka, Norio; Kondoh, T.; Hasegawa, Yutaka

doi:10.1016/s0002-9394(14)72554-1

Cited by 128 publications

(48 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…It is used worldwide in clinical practice for determination of liver blood flow and excretory function, cardiac output and ophthalmic angiography and has even been proposed for intraoperative fluorescent cholangiography [22]. Side effects of ICG are low (<0.5%) [23,24]. Both absorption and fluorescence spectra of ICG peak within the near-infrared range, allowing for the combination with NIR excitation for deep tissue imaging [25].…”

Section: Discussionmentioning

confidence: 99%

Near-infrared confocal imaging during mini-laparoscopy: A novel rigid endomicroscope with increased imaging plane depth

Goetz

Deris

Vieth

et al. 2010

Journal of Hepatology

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

Near-infrared confocal imaging during mini-laparoscopy: A novel rigid endomicroscope with increased imaging plane depth

Goetz

Deris

Vieth

et al. 2010

Journal of Hepatology

View full text Add to dashboard Cite

“…They reported an overall adverse reaction incidence of 0.103%, with hypotension occurring in 0.034% of cases. In a survey done by Takemoto as reported by Obana et al, 14 comprising 57,471 patients from 100 institutions in Japan adverse reactions occurred with frequency of 0.12%.…”

Section: A and A Case Reportsmentioning

confidence: 96%

“…Speich et al 11 have reported that the adverse effects of ICG are dose dependent with a much more frequent incidence when doses exceed 0.5 mg/kg. In a survey of complications associated with ICG angiography during ophthalmic procedures comprising the data from 2918 ICG injections, Obana et al 14 did not find any relationship between ICG dosage and frequency of hypotensive reaction, although the frequency of mild reactions did increase with increasing dosage. They reported an overall adverse reaction incidence of 0.103%, with hypotension occurring in 0.034% of cases.…”

Section: A and A Case Reportsmentioning

confidence: 96%

“…A variety of adverse reactions including death have been reported after the use of ICG in patients with and without any previous exposure 5, [8][9][10][11][12][13][14][15][16] (Table 1). The most commonly reported adverse reactions were typically mild and included pruritus, shortness of breath, and nausea.…”

Section: A and A Case Reportsmentioning

confidence: 99%

“…In the series of complications reported by Speich et al, 11 1 of the patients developed an anaphylactoid reaction to ICG after a previously uneventful injection. Okuda et al were reported by Obana et al 14 to have had a case where the patient developed "shock" during IV ICG administration for a liver function study. This patient had previously undergone the same procedure 4 times without complication.…”

Section: A and A Case Reportsmentioning

confidence: 99%

See 2 more Smart Citations

Occurrence of Severe Hypotension After Indocyanine Green Injection During the Intraoperative Period

2013

View full text Add to dashboard Cite

Indocyanine green (ICG) is generally considered to be safe for IV administration and has a very low incidence of complications. We report 2 cases of severe hypotension immediately after low dose administration of IV ICG. The first case is a 69-year-old woman who developed severe hypotension after a second 5 mg IV bolus of ICG given shortly after the placement of an aneurysm clip during an otherwise uneventful surgery performed under general anesthesia. The second case is a 56-year-old woman with moyamoya disease who became hypotensive subsequent to a 2.5 mg ICG bolus at the conclusion of an external-carotid to internal-carotid bypass procedure under general anesthesia. Anesthesiologists and surgeons are increasingly likely to encounter or request the intraoperative administration of ICG, and they need to be aware of this potential for an adverse reaction, particularly with the repeated doses. Anesthesia and other intraoperative conditions may mask the typically mild adverse reactions usually associated with ICG.

show abstract

Safety of Indocyanine Green Angiography During Pregnancy

Fineman¹

2001

Arch Ophthalmol

View full text Add to dashboard Cite

To establish current practice patterns and assess the general knowledge among vitreoretinaltrained physicians regarding the use of indocyanine green (ICG) angiography during pregnancy, and to review the literature regarding the established safety of ICG angiography in pregnant women. Methods: A survey was mailed to 1101 members of the Retina, Macula, and Vitreous Societies. Results: Of the 520 respondents, 434 (83%) had seen at least 1 pregnant woman who required ICG angiography or fluorescein angiography. Of these, 385 (89%) withheld fluorescein angiography and 105 (24%) withheld ICG angiography, largely because of fear of teratogenicity or lawsuit. Diabetic retinopathy and choroidal neovascular membrane were the most common indications

show abstract

Survey of Complications of Indocyanine Green Angiography in Japan

Cited by 128 publications

References 12 publications

Near-infrared confocal imaging during mini-laparoscopy: A novel rigid endomicroscope with increased imaging plane depth

Near-infrared confocal imaging during mini-laparoscopy: A novel rigid endomicroscope with increased imaging plane depth

Occurrence of Severe Hypotension After Indocyanine Green Injection During the Intraoperative Period

Safety of Indocyanine Green Angiography During Pregnancy

Contact Info

Product

Resources

About