“…We also analyzed the impact of different affiliations on response rate but we found no evidence supporting this influence (interaction test p<0.01). Twenty-one (21) studies were affiliated to healthcare provider, 15,[17][18][19][22][23][24][25][26]28,31,34,35,[37][38][39]41,42,44,46,48 fourteen to academic institutions, 21,27,29,30,32,33,36,40,43,45,47,[49][50][51] one related to regulatory institution 16 and other to the pharmaceutical industry. 20 Heterogeneity could not be explained by this subgroup analysis (I 2 =99% for academic institution affiliation and I 2 =98% for healthcare provider affiliation).…”