Survey on the Effectiveness of Dietary Supplements to Treat Tinnitus

Coelho, Clarisse Simões; Tyler, Richard S.; Ji, Haihong; Rojas-Roncancio, Eveling; Witt, Shelley; Pan, Tao; Jun, Hyung-Jin; Wang, Tang Chuan; Hansen, Marlan R.; Gantz, Bruce J.

doi:10.1044/2016_aja-16-0021

Cited by 26 publications

(17 citation statements)

References 30 publications

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“…To the best of our knowledge, this is the first study that observed the association between less vitamin B 2 intake and tinnitus. Because the role of vitamin B 2 in tinnitus is still debatable and most previous reports of this association are clinical observational studies [ 18 ], we could not find a report that suggested a mechanism for the protective effect of vitamin B 2 on tinnitus. vitamin B 2 is a water-soluble vitamin that participates in transferring electrons in mitochondrial oxidation-reduction reactions [ 19 ].…”

Section: Discussionmentioning

confidence: 71%

Relationship Between Diet and Tinnitus: Korea National Health and Nutrition Examination Survey

Lee

Kim

2018

Clin Exp Otorhinolaryngol

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Objectives This study aimed to analyze the association between nutritional intake and tinnitus prevalence by evaluating a large cross-sectional cohort.Methods Data from the Korea National Health and Nutrition Examination Survey collected between 2013 and 2015 were analyzed. The study population consisted of 7,621 individuals aged 40 to 80 years with complete tinnitus-related data. Individuals with inadequate responses to tinnitus history, noise exposure in the work place, or subjective hearing loss were excluded. Prevalence of tinnitus and tinnitus-related annoyance, and nutrition intake were measured using this questionnaire, and associations between tinnitus and nutritional data were evaluated by binary logistic regression analysis.Results Subjective tinnitus was reported by 1,435 individuals with subjective normal hearing (18.8%). Prevalence of tinnitus increased with age. However, among individuals with tinnitus, the proportion of individuals with tinnitus-related annoyance was similar across age groups. Older age, female sex, lower body mass index (BMI), and less vitamin B2 intake were significantly associated with tinnitus (P<0.001, P=0.002, P=0.041, P=0.013, respectively). Vitamin B2 intake was significantly less in individuals with tinnitus who were middle-aged (ages 51–55 and 56–60 years, P=0.012 and P=0.020, respectively). Less intake of water, protein, and vitamin B3 were associated with tinnitus-related annoyance (P=0.038, P=0.009, and P=0.005, respectively). Prevalence of annoyance was significantly associated with less water intake in younger ages (age 45–55 years) but with less protein and vitamin B3 intake in older ages (age 66–80 years).Conclusion Reduced intake of vitamin B2 and B3, water, and protein may be associated with tinnitus and tinnitus-related annoyance, and further studies regarding the importance of adequate nutritional intake in the tinnitus management need to be performed.

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Section: Discussionmentioning

confidence: 71%

Relationship Between Diet and Tinnitus: Korea National Health and Nutrition Examination Survey

Lee

Kim

2018

Clin Exp Otorhinolaryngol

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“…However, these claims are not supported by the medical literature. AAO–HNS guidelines are clear: “Clinicians should not recommend Ginkgo biloba , melatonin, zinc, or other dietary supplements.” (pS8) Newer studies corroborate these findings regarding dietary supplements . AAO–HNS guidelines warn that these therapies have potential harm and adverse effects in addition to a low likelihood of benefit.…”

Section: Discussionmentioning

confidence: 89%

“…5(pS8) Newer studies corroborate these findings regarding dietary supplements. 23 AAO-HNS guidelines warn that these therapies have potential harm and adverse effects in addition to a low likelihood of benefit. Ironically, some preparations of magnesium salicylate and Salicylum acidum can potentially cause tinnitus.…”

Section: Discussionmentioning

confidence: 99%

Over‐the‐Counter Tinnitus “Cures”: Marketers’ Promises Do Not Ring True

et al. 2018

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Objectives The Clinical Practice Guideline of the American Academy of Otolaryngology–Head & Neck Surgery (2014) stated that clinicians should not recommend dietary supplements for the treatment of tinnitus. The aim of this study is to characterize over‐the‐counter tinnitus remedies (OTCTR) on the U.S. market, describe the ingredients and prices, and characterize the methods of promoting these products. Methods OTCTR were identified via Web search and visits to retail establishments. Information was collected regarding OTCTR chemical composition, product labeling, advertisements and marketing, price, and customers reviews. Results A wide array of unproven OTCTR exist on today's market. All make unfounded claims of relief from ear ringing. Most of the products considered in this study consist of mixtures of inexpensive and common vitamins, minerals, and/or herbs sold at a premium compared to similar preparations not expressly advertised for tinnitus. Certain brands, most notably Arches Tinnitus Formula (Arches Natural Products Inc., Salt Lake City, UT) and Lipo‐Flavonoid (Clarion Brands Inc., Solon, OH), target otolaryngologists by advertising in specialty journals and prominently featuring supposed endorsement by “Ear‐Nose‐and‐Throat Doctors” in their marketing. Conclusion It is important for otolaryngologists who are caring for tinnitus sufferers to be aware that a robust and diverse market exists for unproven OTC tinnitus remedies. It is troubling that heavily advertised brands profess support by otolaryngologists. Responsible specialty organizations in the field should consider opposing such commercially motivated representations. Otolaryngology journals may wish to adopt a policy along the lines of The Journal of the American Medical Association publications to decline advertisements of dietary supplements that make unproven therapeutic claims. Level of Evidence 5 Laryngoscope, 129:1898–1906, 2019

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“…Interestingly, 81% indicated that supplements are ineffective for tinnitus or even make their tinnitus worse. 22 The lack of efficacy is unanimously confirmed by several systematic reviews and existing clinical guidelines for the treatment of tinnitus: dietary supplements or herbs do not improve the symptoms of people with tinnitus and can cause serious side effects, especially if taken along with conventional medications (eg blood thinners, antibiotics). 4,6,7,23,24 Dietary supplements may increase or decrease the effectiveness of medication and alter the results of blood or urine tests.…”

Section: Use Of Dietary Supplementsmentioning

confidence: 99%

Do dietary factors significantly influence tinnitus?

Hofmeister¹

2019

Aust J Gen Pract

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Survey on the Effectiveness of Dietary Supplements to Treat Tinnitus

Cited by 26 publications

References 30 publications

Relationship Between Diet and Tinnitus: Korea National Health and Nutrition Examination Survey

Relationship Between Diet and Tinnitus: Korea National Health and Nutrition Examination Survey

Over‐the‐Counter Tinnitus “Cures”: Marketers’ Promises Do Not Ring True

Do dietary factors significantly influence tinnitus?

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