Survival after surgery for congenital heart defects: Does reduced early mortality predict improved long‐term survival?

Eskedal, Leif; Hagemo, Peter Skjalg; Eskild, Anne; Seiler, Kerry S; Thaulow, Erik

doi:10.1111/j.1651-2227.2005.tb01915.x

Cited by 36 publications

(34 citation statements)

References 18 publications

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“…Over the past decades, advances in diagnostic and surgical techniques and medical treatment of congenital heart disease (ConHD) have gradually evolved and have significantly improved long-term survival of patients with ConHD [1,2].…”

Section: Introductionmentioning

confidence: 99%

Long-term behavioural and emotional problems in four cardiac diagnostic groups of children and adolescents after invasive treatment for congenital heart disease

Spijkerboer¹,

Utens²,

Bogers³

et al. 2008

International Journal of Cardiology

101

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Section: Introductionmentioning

confidence: 99%

Long-term behavioural and emotional problems in four cardiac diagnostic groups of children and adolescents after invasive treatment for congenital heart disease

Spijkerboer¹,

Utens²,

Bogers³

et al. 2008

International Journal of Cardiology

101

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“…Advances in the medical and surgical treatment of patients with congenital heart disease (CHD) have resulted in improved survival, and more children survive to adulthood [1]. Recently, the number of adolescents and adults with CHD has increased rapidly, and in the nearer future, it will exceed that in the children group [2].…”

Section: Introductionmentioning

confidence: 99%

Depression and anxiety in adolescents with congenital heart disease

Awaad¹,

Darahim²

2015

Middle East Current Psychiatry

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IntroductionAdolescents with congenital heart disease (CHD) are at an increased risk of developing psychological distress. Aim of the study The aim of this study was to assess the prevalence of depression and anxiety in adolescents with CHD, and to identify the predictors related to these disorders. Participants and methods This is a cross-sectional case-control study. A total of 60 adolescents with CHD aged between 12 and 18 years and 30 apparently healthy adolescents were recruited. All participants were assessed using a designed questionnaire, the Children's Depression Inventory (CDI), the Revised Children Manifest Anxiety Scale (RCMAS), and the Mini International Neuropsychiatric Interview for Children and Adolescents (MINI-KID). ResultsThe prevalence of depression was higher in adolescents with CHD compared with healthy controls (18.3 vs. 3.3%, P = 0.048). Moreover, 30% of adolescents with CHD had anxiety compared with 10% of the control group (P = 0.03). Multivariate analysis of risk factors showed that the level of education (being illiterate) and the symptomatic cardiac functional class were significant predictors of depression in adolescents with CHD. Likewise, the presence of more than one cardiac defect and having more than one cardiac catheterization were significant predictors of anxiety in adolescents with CHD. Conclusion Adolescents with CHD are at an increased risk of having depression and anxiety, especially those with a low level of education, severe cardiac illness, and multiple cardiac catheterizations. Appropriate psychiatric assessment and early intervention can improve the quality of life of adolescents with CHD.

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“…In addition to a report from our hospital on a subcohort of 970 children operated on for CHD between 1990 and 1999, 7 3 other studies specifically targeting survival after CHD surgery have been published during the past decade, all based on retrospective data. Nieminen et al 5 reported that, among patients <15 years of age who underwent surgery in 1953 to 1989 (75% in 1970-1989), 15-year survival in patients with UVH, TGA, and TOF was 45%, 65%, and 82%, respectively.…”

Section: Survivalmentioning

confidence: 99%

Achievements in Congenital Heart Defect Surgery

Erikssen¹,

Liestøl

Seem³

et al. 2015

Circulation

Self Cite

144

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Background— This article presents an update of the results achieved by modern surgery in congenital heart defects (CHDs) over the past 40 years regarding survival and the need for reoperations, especially focusing on the results from the past 2 decades. Methods and Results— From 1971 to 2011, all 7038 patients <16 years of age undergoing surgical treatment for CHD at Rikshospitalet (Oslo, Norway) were enrolled prospectively. CHD diagnosis, date, and type of all operations were recorded, as was all-cause mortality until December 31, 2012. CHDs were classified as simple (3751/7038=53.2%), complex (2918/7038=41.5%), or miscellaneous (369/7037=5.2%). Parallel to a marked, sequential increase in operations for complex defects, median age at first operation decreased from 1.6 years in 1971 to 1979 to 0.19 years in 2000 to 2011. In total, 1033 died before January 1, 2013. Cumulative survival until 16 years of age in complex CHD operated on in 1971 to 1989 versus 1990 to 2011 was 62.4% versus 86.9% ( P <0.0001). In the comparison of patients operated on in 2000 to 2004 versus 2005 to 2011, 1-year survival was 90.7% versus 96.5% ( P =0.003), and 5-year cumulative survival was 88.8% versus 95.0% ( P =0.0003). In simple versus complex defects, 434 (11.6%) versus 985 (33.8%) patients needed at least 1 reoperation before 16 years of age. In complex defects, 5-year cumulative freedom of reoperation among patients operated on in 1990 to 1999 versus 2000 to 2011 was 66% versus 73% ( P =0.0001). Conclusions— Highly significant, sequential improvements in survival and reductions in reoperations after CHD surgery were seen. A future challenge is to find methods to reduce the need for reoperations and further reduce long-term mortality.

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Survival after surgery for congenital heart defects: Does reduced early mortality predict improved long‐term survival?

Abstract: Early mortality has been substantially reduced in congenital heart defect patients, and corresponds with significantly improved long-term survival.

Cited by 36 publications

References 18 publications

Long-term behavioural and emotional problems in four cardiac diagnostic groups of children and adolescents after invasive treatment for congenital heart disease

Long-term behavioural and emotional problems in four cardiac diagnostic groups of children and adolescents after invasive treatment for congenital heart disease

Depression and anxiety in adolescents with congenital heart disease

Achievements in Congenital Heart Defect Surgery

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