Survival after surgery for oesophageal cancer: a population-based study

Rouvelas, Ioannis; Zeng, Wei; Lindblad, Mats; Viklund, Pernilla; Ye, Weimin; Lagergren, Jesper

doi:10.1016/s1470-2045(05)70347-8

Cited by 178 publications

(185 citation statements)

References 20 publications

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“…These numbers are lower than 5-year survival rates of some other studies (18)(19)(20)(21). However, our study had a limited number of operated patients (169 patients) compared to other large population-based cohorts (18,19). Additionally, ACs (mostly in the second decade) and T3 tumours with lymph node metastases and distant metastases (stages III and IV according to the American Joint Committee on Cancer) -factors which may considerably reduce the 5-year survival ratewere dominant in our series (22).…”

Section: Survivalcontrasting

confidence: 64%

Adenocarcinomas on the Rise — Does it Influence Survival from Oesophageal Cancer?

Goscinski¹,

Larsen²,

Warloe³

et al. 2009

Scand J Surg

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Background and Aims: Asignificant change in the occurrence of oesophageal squamous cell carcinomas (sccs) in relation to adenocarcinomas (Acs) has been observed in the norwegian population during the last 20 years (1988)(1989)(1990)(1991)(1992)(1993)(1994)(1995)(1996)(1997)(1998)(1999)(2000)(2001)(2002)(2003)(2004)(2005)(2006)(2007). the Ac incidence has increased from 5-10% to more than 50% nowadays, while the incidence of sccs has decreased. our goal was to evaluate if the change from scc to Ac and the increased effort to control reflux could be reflected in tumour stage, patient demographics and treatment results. Material and Methods:We analysed clinical and pathological data from 347 patients with oesophageal Ac (n =1 89) and scc (n =1 58) treated at the norwegian radium hospital during said period for patient-and tumour characteristics, treatment modalities and survival.Results: An oesophageal resection was performed in 169 of 347 patients. the median survival rate for all patients was 15 months, with a 5-year survival rate of 10%. the median survival time for operated and non-operated patients was 25 and 12 months respectively, with the corresponding 5-year survival rate of 13% and 2%. patients with n0m0 disease operated with free resection margins presented a 5-year survival rate of 28%.Conclusions: the change from scc to Ac and the ensuing considerable efforts made in surveillance and treatment of Ac did not lead to improved long time survival for our patients.

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Section: Survivalcontrasting

confidence: 64%

Adenocarcinomas on the Rise — Does it Influence Survival from Oesophageal Cancer?

Goscinski¹,

Larsen²,

Warloe³

et al. 2009

Scand J Surg

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show abstract

“…As in other studies (2,3,13), stage was an independent variable of midterm outcome in our analysis. In addition to stage, radicality of surgical resection improves long-term outcome (4); therefore, an eff ort to obtain good surgical margins beyond the neoplastic process and add a thorough lymph node dissection in the resection is advisable.…”

Section: Discussionmentioning

confidence: 64%

“…E sophagectomies are challenging procedures often associated with postoperative complications and prolonged hospital stay. Stage and radicality of resection have traditionally been reported to predict outcomes in patients with primary esophageal carcinoma (1)(2)(3)(4). In addition, other variables such as sex, neoadjuvant treatment, and intensive care unit (ICU) length of stay have been reported to be independent predictors of long-term outcome (4)(5)(6).…”

mentioning

confidence: 99%

Effect of Postoperative Course on Midterm Outcome After Esophageal Resection for Cancer

Chamogeorgakis¹,

Bhora²,

Toumpoulis³

et al. 2013

Baylor University Medical Center Proceedings

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“…Esophageal cancer often has a poor prognosis. Major surgery, including esophagectomy, can offer a 30% chance of cure (Hulscher et al, 2002;Rouvelas et al, 2005). However, such a procedure carries a high risk of severe complications and has a detrimental impact on health-related quality of life (HRQOL) (McCulloch et al, 2003;de Boer et al, 2004;Reynolds et al, 2006;Djärv et al, 2008).…”

Section: Introductionmentioning

confidence: 99%

Association between Physical Activity and Postoperative Complications after Esophagectomy for Cancer: A Prospective Observational Study

Tatematsu¹,

Park²,

Tanaka³

et al. 2013

Asian Pacific Journal of Cancer Prevention

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Survival after surgery for oesophageal cancer: a population-based study

Cited by 178 publications

References 20 publications

Adenocarcinomas on the Rise — Does it Influence Survival from Oesophageal Cancer?

Adenocarcinomas on the Rise — Does it Influence Survival from Oesophageal Cancer?

Effect of Postoperative Course on Midterm Outcome After Esophageal Resection for Cancer

Association between Physical Activity and Postoperative Complications after Esophagectomy for Cancer: A Prospective Observational Study

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