Survival and malformation rate in oocytes and larvae of Cyprinus carpio by exposure to an industrial effluent

Developmental alterations, teratogenic effects, and oxidative disruption induced by ibuprofen, aluminum, and their binary mixture on Danio rerio

“…For example, studies carried out by González-González et al (2014), Martínez-Vieyra et al (2017 and Pérez-Alvarez et al (2018) have found the combined presence of heavy metals (Fe, Al, Hg, As, Cu, Ni, Cr, Cd, Pb) and NSAIDs (DCF, IBP. NPX, PAR) in different water samples of Mexico at concentrations above the maximum levels permitted for the protection of aquatic life with noxious consequences to the biota; as the induction of several toxicity mechanisms at early stages of development (Escobar-Huerfano et al, 2020;Luja-Mondragón et al, 2019;SanJuan-Reyes et al, 2020); Gutiérrez-Noya et al, (2020) found that IBU at environmentally relevant concentrations (1.5-11.5 µg L -1 ) induced major embryonic developmental disorders and teratogenicity on C. carpio oocytes; while, Tenorio-Chávez et al ( 2020) evaluated the lethality and malformations present in zebrafish embryos after exposure to a hospital effluent containing several pharmaceuticals and heavy metals, concluding that these pollutants can promote severe alterations to embryonic development and teratogenic effects.…”