Survival and process outgrowth of human iPSC-derived cells expressing Purkinje cell markers in a mouse model for spinocerebellar degenerative disease

Kamei, Takamasa; Tamada, Atsushi; Kimura, Toshiya; Kakizuka, Akira; Asai, Akio; Muguruma, Keiko

doi:10.1016/j.expneurol.2023.114511

Cited by 6 publications

(1 citation statement)

References 29 publications

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“…The lungs have significant reparative properties when required in response to particular injuries and damage. One of the most reliable hypotheses is that pulmonary tissue might respond to particular stimuli by triggering off stromal cells or by re-starting the cell cycle to regenerate damaged cells [55,56]. Basal cells can operate as tissue-specific stem cells of the airway epithelium in the proximal airway, while in the distal airway, the bronchiolar epithelium is silent until damage happens when variant club cells-representing a group of secretory cells-disclose the ability to proliferate in response to damage [57,58].…”

Section: Regenerative Medicinementioning

confidence: 99%

Mesenchymal Stromal Cell Therapy for Thoracic Surgeons: An Update

Petrella,

Cassina,

Libretti

et al. 2023

JPM

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Stem cells are undifferentiated cells presenting extensive self-renewal features and the ability to differentiate “in vitro” and “in vivo” into a range of lineage cells, like chondrogenic, osteogenic and adipogenic lineages when cultured in specific inducing media. Two major domains of clinical applications of stem cells in thoracic surgery have been investigated: regenerative medicine, which is a section of translational research in tissue engineering focusing on the replacement, renewal or regeneration of cells, tissues and organs to re-establish damaged physiologic functions; drug loading and delivery, representing a new branch proposing stem cells as carriers to provide selected districts with anti-cancer agents for targeted treatments.

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