Survival and quality of life 12 years after ICU. A comparison with the general Norwegian population

Flaatten, Hans; Kvåle, Reidar

doi:10.1007/s001340100960

Cited by 98 publications

(82 citation statements)

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“…However, the collection of in-hospital data and the survival status of individual patients were prospectively registered, and only 52 patients (3% of our entire cohort) were lost to follow-up. Compared with data in other studies, [37][38][39] this number is low. Furthermore, the presence of preadmission disease (comorbid conditions) was determined solely by using the chronic health evaluation component of the original APACHE II.…”

Section: Discussioncontrasting

confidence: 77%

Patients’ Characteristics Associated With Readmission to a Surgical Intensive Care Unit

Timmers

Verhofstad

Moons

et al. 2012

American Journal of Critical Care

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Background Readmission within 48 hours is a leading performance indicator of the quality of care in an intensive care unit. Objective To investigate variables that might be associated with readmission to a surgical intensive care unit. Methods Demographic characteristics, severity-of-illness scores, and survival rates were collected for all patients admitted to a surgical intensive care unit between 1995 and 2000. Long-term survival and quality of life were determined for patients who were readmitted within 30 days after discharge from the unit. Quality of life was measured with the EuroQol-6D questionnaire. Multivariate logistic analysis was used to calculate the independent association of expected covariates. Results Mean follow-up time was 8 years. Of the 1682 patients alive at discharge, 141 (8%) were readmitted. The main causes of readmission were respiratory decompensation (48%) and cardiac conditions (16%). Compared with the total sample, patients readmitted were older, mostly had vascular (39%) or gastrointestinal (26%) disease, and had significantly higher initial severity of illness (P = .003, .007) and significantly more comorbid conditions (P = .005). For all surgical classifications except general surgery, readmission was independently associated with type of admission and need for mechanical ventilation. Long-term mortality was higher among patients who were readmitted than among the total sample. Nevertheless, quality-of-life scores were the same for patients who were readmitted and patients who were not. Conclusion The adverse effect of readmission to the intensive care unit on survival appears to be long-lasting, and predictors of readmission are scarce.

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Section: Discussioncontrasting

confidence: 77%

Patients’ Characteristics Associated With Readmission to a Surgical Intensive Care Unit

Timmers

Verhofstad

Moons

et al. 2012

American Journal of Critical Care

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“…In these investigations the cohort was found to be comparable to other general ICU follow-up studies in Scandinavia and in northern Europe. Also the background characteristics (APACHE II, LoS, diagnoses) are similar in comparison [3,27,32]. It may therefore be assumed that the findings presented in this study regarding the effects of social support are valid also for other units in this part of the world.…”

Section: Discussionmentioning

confidence: 58%

“…A decreased HRQoL has repeatedly been shown for former ICU patients both short and long term after critical care and compared with a general population [3][4][5]. Focus in such studies has been directed at factors believed to be important for this outcome.…”

Section: Introduction (Paper Length Words 3013 )mentioning

confidence: 99%

Social integration: an important factor for health-related quality of life after critical illness

et al. 2011

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(Abstract length words 200)Objectives: To examine to what extent availability of social integration affect health related quality of life (HRQoL) in former Intensive Care Unit (ICU) patients and how it relates to corresponding findings in a general reference group.Design: Controlled, multicenter, prospective, explorative study. Setting and Patients:HRQoL data (SF-36) was collected from three combined medical and surgical intensive care units in the southeast of Sweden. Social integration was assessed by the Availability of Social Integration (AVSI) instrument (7 questions related to the social interaction of the patient). As reference group, a random sample (n=6093) of people from the uptake area of the hospitals were used. Social integration (AVSI), HRQoL (SF-36), and comorbidity was examined also in the reference group.Interventions: None. Measurements and results:The level of social integration significantly affected HRQoL for the former ICU patients whereas no such effect was seen for the general reference group. For the ICU patients' social integration affected HRQoL to a larger extent than age, sex and the ICU related factors examined, but to a lower extent than the pre-existing diseases.Conclusions: For a comprehensive assessment of HRQoL in former ICU patients it is mandatory to include the effect of social integration. .

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“…The time taken for the survival of ICU patients to match that of an age-and sex-matched population varies, particularly with diagnosis. European results [33] suggest that paralleling the age-and sexmatched population may occur earlier, but because of the greater severity of illness in ICU patients in the UK, such paralleling may take longer. Results from Glasgow suggest after 5 years the survival of critically ill patients may indeed be better than the age-and sexmatched normal population [34].…”

Section: Discussionmentioning

confidence: 97%

Cost effectiveness of adult intensive care in the UK

Ridley

Morris

2007

Anaesthesia

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SummaryWe wished to investigate whether intensive care represents good value for money to the National Health Service in the UK using cost-effectiveness analysis. We developed a cost-effectiveness model using secondary data sources to estimate the incremental cost per quality adjusted life year gained of treatment in intensive care vs non-intensive care treatment in adults. Estimates of hospital mortality with and without intensive care were obtained from seven published studies and from data published by the Intensive Care National Audit and Research Centre. Quality of life estimates were obtained from a literature review and NHS reference costs were used. Relative to nonintensive care treatment, the incremental cost per quality adjusted life year gained of treatment in intensive care is £7010. This figure is sensitive to the mortality risk reduction associated with intensive care. Despite the high daily cost of intensive care, its cost-effectiveness is excellent and compares favourably with other commonly used health interventions. Our findings suggest that adult intensive care represents good value for money.

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Survival and quality of life 12 years after ICU. A comparison with the general Norwegian population

Abstract: Our findings indicate that the long-term outcome after ICU is good, with an acceptable QOL and a life expectancy comparable with the general population in survivors 2 years after the ICU stay.

Cited by 98 publications

References 0 publications

Patients’ Characteristics Associated With Readmission to a Surgical Intensive Care Unit

Patients’ Characteristics Associated With Readmission to a Surgical Intensive Care Unit

Social integration: an important factor for health-related quality of life after critical illness

Cost effectiveness of adult intensive care in the UK

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