2019
DOI: 10.1002/jgh3.12290
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Survival benefit associated with early detection of spontaneous bacterial peritonitis in veteran inpatients with cirrhotic ascites

Abstract: Background Spontaneous bacterial peritonitis (SBP) is common in hospitalized cirrhotic patients with ascites and carries high mortality. This study aimed to determine whether early diagnostic paracentesis (EDP) <12 h of hospitalization conveys an intermediate‐term (6‐month) survival benefit in cirrhotic patients diagnosed with SBP. Methods Consecutive US veterans with cirrhosis diagnosed with SBP over 13 years at a single VA medical center were reviewed retrospectively. Kaplan‐Meyer analyses assessed the effec… Show more

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Cited by 3 publications
(9 citation statements)
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“…Although DP did not definitively influenced mortality rates or LOS, a clinically significant increase in LOS trended toward DP procedures, consistent with other studies [11][12][13]28]. We also found 80.7% of patients received antibiotics prior to paracentesis.…”
Section: Discussionsupporting
confidence: 90%
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“…Although DP did not definitively influenced mortality rates or LOS, a clinically significant increase in LOS trended toward DP procedures, consistent with other studies [11][12][13]28]. We also found 80.7% of patients received antibiotics prior to paracentesis.…”
Section: Discussionsupporting
confidence: 90%
“…Studies with larger populations are necessary to detect further differences with statistical significance. Nonetheless, our population size in a five-year period is comparable with other published literature assessing patients with SBP [10,11,[24][25][26][27][28][29]. Karvellas et al [11] analyzed aspects of antimicrobial therapy to mortality in patients with SBP from an international multicenter database over a 15-year time span, yielding a cohort of 126 patients.…”
Section: Discussionsupporting
confidence: 67%
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