Survival Benefit of Radiofrequency Ablation with Intratumoral Cisplatin Administration in a Rabbit VX2 Lung Tumor Model

Murai, Kazuki; Hamamoto, Shinichi; Okuma, Tomohisa; Kageyama, Ken; Yamamoto, Akira; Ogawa, Satoyuki; Nota, Takehito; Sohgawa, Etsuji; Jogo, Atsushi; Miki, Yukio

doi:10.1007/s00270-020-02686-0

Cited by 2 publications

(1 citation statement)

References 27 publications

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“…Rabbits are easy to maintain and rabbit models are cost-effective and have satisfactory repeatability and operability. A variety of preclinical rabbit models have been widely reported (48)(49)(50). In these models, the auxiliary examinations of the human body, such as ultrasound, CT, MRI and endoscopy, are able to be successfully simulated.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of animal models of Crohn's disease with anal fistula (Review)

Zhu

Guo

et al. 2021

Exp Ther Med

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Anal fistula is a common and serious complication of Crohn's disease (CD). A sufficiently suitable animal model that may be used to simulate this disease is yet to be established. The aim of the present review was to summarize the different characteristics and experimental methods of commonly used animal models of CD with anal fistula. Electronic databases were searched for studies reporting on the use of this type of animal model. A total of 234 related articles were retrieved, of which six articles met the inclusion criteria; these were used as references for the present review article. The characteristics of the animal models, the advantages and disadvantages of the modeling methods and the similarities with patients with CD and anal fistula were summarized and analyzed. The evidence suggests that a sufficiently suitable animal preclinical model requires to be established.

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Section: Discussionmentioning

confidence: 99%