Survival in malnourished older patients receiving post-discharge nutritional support; long-term results of a randomized controlled trial

Abstract

The current study failed to show an effect of a three-months post-discharge multi-component nutritional intervention in malnourished older patients on long-term survival, despite the positive effects on short-term outcome such as functional limitations and falls.

Is telehealth effective in managing malnutrition in community-dwelling older adults? A systematic review and meta-analysis

“…Lindhardt et al [28] provided participants with an internet-enabled tablet, preloaded with an application which allowed them to order meals three times per week, and provided automated feedback on how intake corresponded with individual energy and protein requirements. Only one intervention, reported across four publications by Neelemaat et al [34,[37][38][39], provided all participants with oral nutritional supplements; whereas five other studies provided them on a case-by-case basis to align with an individualised plan [27,30,32,33,35,36].…”

ESPEN guideline on clinical nutrition and hydration in geriatrics

“…In addition costeffectiveness of the intervention was shown [64]. No effects were found regarding body weight, fat free mass, handgrip strength as well as 1-and 4-year mortality [63,65]. Beck et al [66,67] conducted a multi-facet intervention in nursing home residents consisting of home-made nutritional supplements, oral care and group exercise resulting in improved protein intake, body weight, physical performance and social activity.…”

Effectiveness of dietary counseling with or without nutrition supplementation in hospitalized patients who are malnourished or at risk of malnutrition: A systematic review and meta‐analysis

“…Seven studies reported hospital LOS. 21,22,24,26,27,29,33 Figure 3B shows the meta-analysis of the pooled effect size for LOS 21,24,27,29,33,37 (mean difference: −0.75 days; 95% CI, −1.66 to 0.17; I 2 = 70%; P = 0.11; GRADE: low certainty). Removing one study 29 (in which the mean LOS was calculated from median with IQR) reduced the heterogeneity to 27% but made little difference to the mean difference.…”

“…Sixteen studies 16,[19][20][21][22][23][24][25][26][27][28][29][30][31][32][33] met the inclusion criteria of our review and underwent data extraction. We also included data from the five post hoc study publications [34][35][36][37][38] by Neelemaat et al, 26 Scheutz et al, 27 and Söderström et al, 30 as they contained outcome data relevant to this meta-analysis. 28,32 The study characteristics are depicted in Table 1.…”

“…Various mortality outcomes at different time points were measured in the selected studies. Five studies reported inpatient to 30-day mortality, 20,24,26,27,29 5 reported 3-month mortality, 19,29,31,33,37 2 reported 4-month mortality, 16,31 12 reported 6-month mortality, [19][20][21][22][23][24]29,30,[32][33][34]37 and 4 reported 1-year mortality outcomes. 20,29,30,37 We derived 3-month and 6-month mortality rates from Kaplan-Meier curves from Sharma et al 29 and Bonilla-Paloma et al 20 In addition, we contacted Söderström et al 30 for the 6-month mortality figures and received a response.…”