2010
DOI: 10.1001/archophthalmol.2010.121
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Survival in Patients With Presymptomatic Diagnosis of Metastatic Uveal Melanoma

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Cited by 52 publications
(28 citation statements)
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“…The value of screening has been questioned, because treatment for metastasis only rarely prolongs life [9,10]; however, therapeutic methods are advancing rapidly. There is some evidence that screening may nevertheless improve patients' well-being because a normal test result provides reassurance that health is unlikely to deteriorate in the near future.…”
Section: Discussionmentioning
confidence: 99%
“…The value of screening has been questioned, because treatment for metastasis only rarely prolongs life [9,10]; however, therapeutic methods are advancing rapidly. There is some evidence that screening may nevertheless improve patients' well-being because a normal test result provides reassurance that health is unlikely to deteriorate in the near future.…”
Section: Discussionmentioning
confidence: 99%
“…[4][5][6][7][8][9] These patients typically participated in surveillance for early detection of asymptomatic metastases so that lead time bias likely contributed to their survival times. 10,11 For example, patients reviewed annually with abdominal ultrasonography to detect hepatic metastases, the predominant type of metastasis from uveal melanoma, [12][13][14] survived a median of 5 months longer than those who were not screened, but their survival times from diagnosis of the primary tumor to death did not differ. 3 Because uveal melanoma is rare, few randomized clinical trials are performed.…”
Section: A N U S C R I P Tmentioning
confidence: 99%
“…65 However, new therapies have recently improved survival prospects but are more likely to be effective if undertaken before symptomatic disease develops. Screening also enhances the quality of life of high-risk patients, a normal result reassuring them that they will enjoy good health for many months, at least until the next scan is performed.…”
Section: Screening For Metastatic Diseasementioning
confidence: 99%