Survival of<i>Lactobacillus casei</i>in the Human Digestive Tract after Consumption of Fermented Milk

Oozeer, Raish; Leplingard, Antony; Mater, Denis D.G.; Mogenet, Agnès; Michelin, Rachel; Seksek, Isabelle; Marteau, Philippe; Doré, Joël; Bresson, Jean-Louis; Corthier, Gérard

doi:10.1128/aem.00722-06

Cited by 91 publications

(63 citation statements)

References 22 publications

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“…L. casei Shirota cells have been found in the feces of human volunteers receiving fermented milk containing L. casei . L. casei DN-114 001 cells have been found in ileal and fecal samples of human volunteers receiving fermented milk containing L. casei DN-114 001 or the derived L. casei strain DN-114 001Rif (279,280). In human adult volunteers and infants, L. reuteri ATCC 55730 cells have been found in fecal samples (275,281,282).…”

Section: Clinical Studiesmentioning

confidence: 88%

Anti-Infective Activities of Lactobacillus Strains in the Human Intestinal Microbiota: from Probiotics to Gastrointestinal Anti-Infectious Biotherapeutic Agents

2014

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SUMMARY A vast and diverse array of microbial species displaying great phylogenic, genomic, and metabolic diversity have colonized the gastrointestinal tract. Resident microbes play a beneficial role by regulating the intestinal immune system, stimulating the maturation of host tissues, and playing a variety of roles in nutrition and in host resistance to gastric and enteric bacterial pathogens. The mechanisms by which the resident microbial species combat gastrointestinal pathogens are complex and include competitive metabolic interactions and the production of antimicrobial molecules. The human intestinal microbiota is a source from which Lactobacillus probiotic strains have often been isolated. Only six probiotic Lactobacillus strains isolated from human intestinal microbiota, i.e., L. rhamnosus GG, L. casei Shirota YIT9029, L. casei DN-114 001, L. johnsonii NCC 533, L. acidophilus LB, and L. reuteri DSM 17938, have been well characterized with regard to their potential antimicrobial effects against the major gastric and enteric bacterial pathogens and rotavirus. In this review, we describe the current knowledge concerning the experimental antibacterial activities, including antibiotic-like and cell-regulating activities, and therapeutic effects demonstrated in well-conducted, placebo-controlled, randomized clinical trials of these probiotic Lactobacillus strains. What is known about the antimicrobial activities supported by the molecules secreted by such probiotic Lactobacillus strains suggests that they constitute a promising new source for the development of innovative anti-infectious agents that act luminally and intracellularly in the gastrointestinal tract.

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Section: Clinical Studiesmentioning

confidence: 88%

Anti-Infective Activities of Lactobacillus Strains in the Human Intestinal Microbiota: from Probiotics to Gastrointestinal Anti-Infectious Biotherapeutic Agents

2014

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“…low pH, exposure to enzymes and bile) was measured and compared to untreated bacteria growth. No significant differences were observed between the two sets of results, indicating that the bacteria are able to withstand the harsh physiological conditions (Table 2) [17,29]. Proinflammatory cytokine production was measured fol- lowing co-cultured of GIT-simulated bacteria with the different cells as above.…”

Section: Cytokine Secretion Induced By Mock Git-subjected Bacteriamentioning

confidence: 99%

Cytokine profile and induction of T helper type 17 and regulatory T cells by human peripheral mononuclear cells after microbial exposure

Donkor

Ravikumar

Proudfoot

et al. 2012

Clinical and Experimental Immunology

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“…Strains which were utilized for fermentation of milk have a good opportunity to survive because some probiotics survives better when investigated in fermented milk (Pochart et al, 1992). Survival rates of Lactobacillus casei DN-114 001 ingested in fermented milk were up to 51.2% in the ileum and 28.4% in the feces (Oozeer et al, 2006). Consumption of yogurt and fermented milk products containing LAB/probiotics influence the increase of their number in fecal samples (Rochet et al, 2000;Yuki et al, 1999).…”

Section: Quantity Of Lead In Faecesmentioning

confidence: 99%

Protection against lead contamination by strains of lactic acid bacteria from<br>fermented camel milk

Akhmetsadykova¹,

Konuspayeva²,

Loiseau³

et al. 2013

Emir. J. Food Agric

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The effectiveness of the fermented milk product for decreasing the absorption of Lead (Pb) in vivo by testing several combinations of different strains and individual strains of LAB isolated from camel milk and shubat (fermented camel milk) was determined. During 4 weeks 0.5 ppm of Pb was given to cavies in fermented milk product and water. Control group and groups treated only by fermented milk products, also, were observed. Faeces, Blood, Heart, Lungs, Liver, Kidneys, and Spleen were analyzed. The lead concentrations in faeces of Control group and lead nitrate treated group were nearly the same. The quantity of Pb in faeces of fermented milk treated groups was higher than in Control and Water Pb groups. In the different cavies' organs of Water Pb group, the higher concentration of heavy metal (ppm) was observed in spleen (1.04), heart (0.65), kidneys (0.58), and blood (0.46) to be compared to 0.82, 0.2, 0.58 and 0.31 respectively in control group. In groups treated with fermented milk without/with Pb, the lead concentration decreased in target organs. Quantity of lead in blood samples of Control group and groups treated fermented milk products without/with Pb is nearly same. Highest concentration of blood Pb was observed for Water Pb group.

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Survival ofLactobacillus caseiin the Human Digestive Tract after Consumption of Fermented Milk

Cited by 91 publications

References 22 publications

Anti-Infective Activities of Lactobacillus Strains in the Human Intestinal Microbiota: from Probiotics to Gastrointestinal Anti-Infectious Biotherapeutic Agents

Anti-Infective Activities of Lactobacillus Strains in the Human Intestinal Microbiota: from Probiotics to Gastrointestinal Anti-Infectious Biotherapeutic Agents

Cytokine profile and induction of T helper type 17 and regulatory T cells by human peripheral mononuclear cells after microbial exposure

Protection against lead contamination by strains of lactic acid bacteria from<br>fermented camel milk

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